Search Results for author: Tairan Liu

Found 17 papers, 0 papers with code

Virtual histological staining of unlabeled autopsy tissue

no code implementations2 Aug 2023 Yuzhu Li, Nir Pillar, Jingxi Li, Tairan Liu, Di wu, Songyu Sun, Guangdong Ma, Kevin De Haan, Luzhe Huang, Sepehr Hamidi, Anatoly Urisman, Tal Keidar Haran, William Dean Wallace, Jonathan E. Zuckerman, Aydogan Ozcan

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation of cadaver tissue, as well as the resource-intensive nature of chemical staining procedures covering large tissue areas, which demand substantial labor, cost, and time.

Image Registration

eFIN: Enhanced Fourier Imager Network for generalizable autofocusing and pixel super-resolution in holographic imaging

no code implementations9 Jan 2023 Hanlong Chen, Luzhe Huang, Tairan Liu, Aydogan Ozcan

The application of deep learning techniques has greatly enhanced holographic imaging capabilities, leading to improved phase recovery and image reconstruction.

Image Reconstruction Super-Resolution

Self-supervised learning of hologram reconstruction using physics consistency

no code implementations17 Sep 2022 Luzhe Huang, Hanlong Chen, Tairan Liu, Aydogan Ozcan

Here, we report a self-supervised learning model, termed GedankenNet, that eliminates the need for labeled or experimental training data, and demonstrate its effectiveness and superior generalization on hologram reconstruction tasks.

Image Reconstruction Self-Supervised Learning

Virtual impactor-based label-free bio-aerosol detection using holography and deep learning

no code implementations30 Aug 2022 Yi Luo, Yijie Zhang, Tairan Liu, Alan Yu, Yichen Wu, Aydogan Ozcan

To address this need, we present a mobile and cost-effective label-free bio-aerosol sensor that takes holographic images of flowing particulate matter concentrated by a virtual impactor, which selectively slows down and guides particles larger than ~6 microns to fly through an imaging window.

Virtual stain transfer in histology via cascaded deep neural networks

no code implementations14 Jul 2022 Xilin Yang, Bijie Bai, Yijie Zhang, Yuzhu Li, Kevin De Haan, Tairan Liu, Aydogan Ozcan

Unlike a single neural network structure which only takes one stain type as input to digitally output images of another stain type, C-DNN first uses virtual staining to transform autofluorescence microscopy images into H&E and then performs stain transfer from H&E to the domain of the other stain in a cascaded manner.

Virtual staining of defocused autofluorescence images of unlabeled tissue using deep neural networks

no code implementations6 Jul 2022 Yijie Zhang, Luzhe Huang, Tairan Liu, Keyi Cheng, Kevin De Haan, Yuzhu Li, Bijie Bai, Aydogan Ozcan

Here, we introduce a fast virtual staining framework that can stain defocused autofluorescence images of unlabeled tissue, achieving equivalent performance to virtual staining of in-focus label-free images, also saving significant imaging time by lowering the microscope's autofocusing precision.

Collaborative Inference

Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning

no code implementations30 Jun 2022 Tairan Liu, Yuzhu Li, Hatice Ceylan Koydemir, Yijie Zhang, Ethan Yang, Merve Eryilmaz, Hongda Wang, Jingxi Li, Bijie Bai, Guangdong Ma, Aydogan Ozcan

We also demonstrated that this data-driven plaque assay offers the capability of quantifying the infected area of the cell monolayer, performing automated counting and quantification of PFUs and virus-infected areas over a 10-fold larger dynamic range of virus concentration than standard viral plaque assays.

Specificity Virology

Deep Learning-enabled Detection and Classification of Bacterial Colonies using a Thin Film Transistor (TFT) Image Sensor

no code implementations7 May 2022 Yuzhu Li, Tairan Liu, Hatice Ceylan Koydemir, Hongda Wang, Keelan O'Riordan, Bijie Bai, Yuta Haga, Junji Kobashi, Hitoshi Tanaka, Takaya Tamaru, Kazunori Yamaguchi, Aydogan Ozcan

Due to the large scalability, ultra-large field-of-view, and low cost of the TFT-based image sensors, this platform can be integrated with each agar plate to be tested and disposed of after the automated CFU count.

Cultural Vocal Bursts Intensity Prediction

Fourier Imager Network (FIN): A deep neural network for hologram reconstruction with superior external generalization

no code implementations22 Apr 2022 Hanlong Chen, Luzhe Huang, Tairan Liu, Aydogan Ozcan

Deep learning-based image reconstruction methods have achieved remarkable success in phase recovery and holographic imaging.

Image Reconstruction

Few-shot Transfer Learning for Holographic Image Reconstruction using a Recurrent Neural Network

no code implementations27 Jan 2022 Luzhe Huang, Xilin Yang, Tairan Liu, Aydogan Ozcan

Here, we demonstrate a few-shot transfer learning method that helps a holographic image reconstruction deep neural network rapidly generalize to new types of samples using small datasets.

Image Reconstruction Transfer Learning

Neural network-based image reconstruction in swept-source optical coherence tomography using undersampled spectral data

no code implementations4 Mar 2021 Yijie Zhang, Tairan Liu, Manmohan Singh, Yilin Luo, Yair Rivenson, Kirill V. Larin, Aydogan Ozcan

Using 2-fold undersampled spectral data (i. e., 640 spectral points per A-line), the trained neural network can blindly reconstruct 512 A-lines in ~6. 73 ms using a desktop computer, removing spatial aliasing artifacts due to spectral undersampling, also presenting a very good match to the images of the same samples, reconstructed using the full spectral OCT data (i. e., 1280 spectral points per A-line).

Image Reconstruction

Deep learning-based transformation of the H&E stain into special stains

no code implementations20 Aug 2020 Kevin de Haan, Yijie Zhang, Jonathan E. Zuckerman, Tairan Liu, Anthony E. Sisk, Miguel F. P. Diaz, Kuang-Yu Jen, Alexander Nobori, Sofia Liou, Sarah Zhang, Rana Riahi, Yair Rivenson, W. Dean Wallace, Aydogan Ozcan

Based on evaluation by three renal pathologists, followed by adjudication by a fourth renal pathologist, we show that the generation of virtual special stains from existing H&E images improves the diagnosis in several non-neoplastic kidney diseases sampled from 58 unique subjects.

Deep learning-based holographic polarization microscopy

no code implementations1 Jul 2020 Tairan Liu, Kevin de Haan, Bijie Bai, Yair Rivenson, Yi Luo, Hongda Wang, David Karalli, Hongxiang Fu, Yibo Zhang, John FitzGerald, Aydogan Ozcan

Our analysis shows that a trained deep neural network can extract the birefringence information using both the sample specific morphological features as well as the holographic amplitude and phase distribution.

Medical Diagnosis

Deep learning-based color holographic microscopy

no code implementations15 Jul 2019 Tairan Liu, Zhensong Wei, Yair Rivenson, Kevin De Haan, Yibo Zhang, Yichen Wu, Aydogan Ozcan

We report a framework based on a generative adversarial network (GAN) that performs high-fidelity color image reconstruction using a single hologram of a sample that is illuminated simultaneously by light at three different wavelengths.

Generative Adversarial Network Image Reconstruction

Deep learning-based super-resolution in coherent imaging systems

no code implementations15 Oct 2018 Tairan Liu, Kevin De Haan, Yair Rivenson, Zhensong Wei, Xin Zeng, Yibo Zhang, Aydogan Ozcan

We present a deep learning framework based on a generative adversarial network (GAN) to perform super-resolution in coherent imaging systems.

Generative Adversarial Network Image Reconstruction +1

PhaseStain: Digital staining of label-free quantitative phase microscopy images using deep learning

no code implementations20 Jul 2018 Yair Rivenson, Tairan Liu, Zhensong Wei, Yibo Zhang, Aydogan Ozcan

Using a deep neural network, we demonstrate a digital staining technique, which we term PhaseStain, to transform quantitative phase images (QPI) of labelfree tissue sections into images that are equivalent to brightfield microscopy images of the same samples that are histochemically stained.

Generative Adversarial Network

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