Virtual histological staining of unlabeled autopsy tissue

no code implementations • 2 Aug 2023 • Yuzhu Li, Nir Pillar, Jingxi Li, Tairan Liu, Di wu, Songyu Sun, Guangdong Ma, Kevin De Haan, Luzhe Huang, Sepehr Hamidi, Anatoly Urisman, Tal Keidar Haran, William Dean Wallace, Jonathan E. Zuckerman, Aydogan Ozcan

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation of cadaver tissue, as well as the resource-intensive nature of chemical staining procedures covering large tissue areas, which demand substantial labor, cost, and time.

Image Registration

Unidirectional Imaging using Deep Learning-Designed Materials

no code implementations • 5 Dec 2022 • Jingxi Li, Tianyi Gan, Yifan Zhao, Bijie Bai, Che-Yung Shen, Songyu Sun, Mona Jarrahi, Aydogan Ozcan

A unidirectional imager would only permit image formation along one direction, from an input field-of-view (FOV) A to an output FOV B, and in the reverse path, the image formation would be blocked.

Blocking