Search Results for author: Nir Pillar

Found 5 papers, 0 papers with code

Autonomous Quality and Hallucination Assessment for Virtual Tissue Staining and Digital Pathology

no code implementations29 Apr 2024 Luzhe Huang, Yuzhu Li, Nir Pillar, Tal Keidar Haran, William Dean Wallace, Aydogan Ozcan

Here, we present an autonomous quality and hallucination assessment method (termed AQuA), mainly designed for virtual tissue staining, while also being applicable to histochemical staining.

Hallucination Image Generation

Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling

no code implementations1 Apr 2024 Sahan Yoruc Selcuk, Xilin Yang, Bijie Bai, Yijie Zhang, Yuzhu Li, Musa Aydin, Aras Firat Unal, Aditya Gomatam, Zhen Guo, Darrow Morgan Angus, Goren Kolodney, Karine Atlan, Tal Keidar Haran, Nir Pillar, Aydogan Ozcan

Human epidermal growth factor receptor 2 (HER2) is a critical protein in cancer cell growth that signifies the aggressiveness of breast cancer (BC) and helps predict its prognosis.

Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning

no code implementations14 Mar 2024 Xilin Yang, Bijie Bai, Yijie Zhang, Musa Aydin, Sahan Yoruc Selcuk, Zhen Guo, Gregory A. Fishbein, Karine Atlan, William Dean Wallace, Nir Pillar, Aydogan Ozcan

Systemic amyloidosis is a group of diseases characterized by the deposition of misfolded proteins in various organs and tissues, leading to progressive organ dysfunction and failure.

Virtual histological staining of unlabeled autopsy tissue

no code implementations2 Aug 2023 Yuzhu Li, Nir Pillar, Jingxi Li, Tairan Liu, Di wu, Songyu Sun, Guangdong Ma, Kevin De Haan, Luzhe Huang, Sepehr Hamidi, Anatoly Urisman, Tal Keidar Haran, William Dean Wallace, Jonathan E. Zuckerman, Aydogan Ozcan

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation of cadaver tissue, as well as the resource-intensive nature of chemical staining procedures covering large tissue areas, which demand substantial labor, cost, and time.

Image Registration

Deep Learning-enabled Virtual Histological Staining of Biological Samples

no code implementations13 Nov 2022 Bijie Bai, Xilin Yang, Yuzhu Li, Yijie Zhang, Nir Pillar, Aydogan Ozcan

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic assessment of tissue.

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