Search Results for author: Luzhe Huang

Found 13 papers, 0 papers with code

Autonomous Quality and Hallucination Assessment for Virtual Tissue Staining and Digital Pathology

no code implementations29 Apr 2024 Luzhe Huang, Yuzhu Li, Nir Pillar, Tal Keidar Haran, William Dean Wallace, Aydogan Ozcan

Here, we present an autonomous quality and hallucination assessment method (termed AQuA), mainly designed for virtual tissue staining, while also being applicable to histochemical staining.

Hallucination Image Generation

Neural Network-Based Processing and Reconstruction of Compromised Biophotonic Image Data

no code implementations21 Mar 2024 Michael John Fanous, Paloma Casteleiro Costa, Cagatay Isil, Luzhe Huang, Aydogan Ozcan

The integration of deep learning techniques with biophotonic setups has opened new horizons in bioimaging.

Virtual histological staining of unlabeled autopsy tissue

no code implementations2 Aug 2023 Yuzhu Li, Nir Pillar, Jingxi Li, Tairan Liu, Di wu, Songyu Sun, Guangdong Ma, Kevin De Haan, Luzhe Huang, Sepehr Hamidi, Anatoly Urisman, Tal Keidar Haran, William Dean Wallace, Jonathan E. Zuckerman, Aydogan Ozcan

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation of cadaver tissue, as well as the resource-intensive nature of chemical staining procedures covering large tissue areas, which demand substantial labor, cost, and time.

Image Registration

Cycle Consistency-based Uncertainty Quantification of Neural Networks in Inverse Imaging Problems

no code implementations22 May 2023 Luzhe Huang, Jianing Li, Xiaofu Ding, Yijie Zhang, Hanlong Chen, Aydogan Ozcan

Uncertainty estimation is critical for numerous applications of deep neural networks and draws growing attention from researchers.

Deblurring Image Deblurring +2

eFIN: Enhanced Fourier Imager Network for generalizable autofocusing and pixel super-resolution in holographic imaging

no code implementations9 Jan 2023 Hanlong Chen, Luzhe Huang, Tairan Liu, Aydogan Ozcan

The application of deep learning techniques has greatly enhanced holographic imaging capabilities, leading to improved phase recovery and image reconstruction.

Image Reconstruction Super-Resolution

Self-supervised learning of hologram reconstruction using physics consistency

no code implementations17 Sep 2022 Luzhe Huang, Hanlong Chen, Tairan Liu, Aydogan Ozcan

Here, we report a self-supervised learning model, termed GedankenNet, that eliminates the need for labeled or experimental training data, and demonstrate its effectiveness and superior generalization on hologram reconstruction tasks.

Image Reconstruction Self-Supervised Learning

Virtual staining of defocused autofluorescence images of unlabeled tissue using deep neural networks

no code implementations6 Jul 2022 Yijie Zhang, Luzhe Huang, Tairan Liu, Keyi Cheng, Kevin De Haan, Yuzhu Li, Bijie Bai, Aydogan Ozcan

Here, we introduce a fast virtual staining framework that can stain defocused autofluorescence images of unlabeled tissue, achieving equivalent performance to virtual staining of in-focus label-free images, also saving significant imaging time by lowering the microscope's autofocusing precision.

Collaborative Inference

Fourier Imager Network (FIN): A deep neural network for hologram reconstruction with superior external generalization

no code implementations22 Apr 2022 Hanlong Chen, Luzhe Huang, Tairan Liu, Aydogan Ozcan

Deep learning-based image reconstruction methods have achieved remarkable success in phase recovery and holographic imaging.

Image Reconstruction

Few-shot Transfer Learning for Holographic Image Reconstruction using a Recurrent Neural Network

no code implementations27 Jan 2022 Luzhe Huang, Xilin Yang, Tairan Liu, Aydogan Ozcan

Here, we demonstrate a few-shot transfer learning method that helps a holographic image reconstruction deep neural network rapidly generalize to new types of samples using small datasets.

Image Reconstruction Transfer Learning

Deep learning-based virtual refocusing of images using an engineered point-spread function

no code implementations22 Dec 2020 Xilin Yang, Luzhe Huang, Yilin Luo, Yichen Wu, Hongda Wang, Yair Rivenson, Aydogan Ozcan

We present a virtual image refocusing method over an extended depth of field (DOF) enabled by cascaded neural networks and a double-helix point-spread function (DH-PSF).

Image Reconstruction

Recurrent neural network-based volumetric fluorescence microscopy

no code implementations21 Oct 2020 Luzhe Huang, Yilin Luo, Yair Rivenson, Aydogan Ozcan

Volumetric imaging of samples using fluorescence microscopy plays an important role in various fields including physical, medical and life sciences.

Image Reconstruction

Single-shot autofocusing of microscopy images using deep learning

no code implementations21 Mar 2020 Yilin Luo, Luzhe Huang, Yair Rivenson, Aydogan Ozcan

We demonstrate a deep learning-based offline autofocusing method, termed Deep-R, that is trained to rapidly and blindly autofocus a single-shot microscopy image of a specimen that is acquired at an arbitrary out-of-focus plane.

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