Three-component contour dynamics model to simulate and analyze amoeboid cell motility

no code implementations • 24 Oct 2022 • Daniel Schindler, Ted Moldenhawer, Carsten Beta, Wilhelm Huisinga, Matthias Holschneider

The model is used to generate contour data for a variety of qualitatively different, e. g., polarized and non-polarized, cell tracks that are hardly distinguishable from experimental data.

Analysis of protrusion dynamics in amoeboid cell motility by means of regularized contour flows

no code implementations • 26 May 2020 • Daniel Schindler, Ted Moldenhawer, Maike Stange, Valentino Lepro, Carsten Beta, Matthias Holschneider, Wilhelm Huisinga

Amoeboid cell motility is essential for a wide range of biological processes including wound healing, embryonic morphogenesis, and cancer metastasis.