Search Results for author: Yuchi Qiu

Found 7 papers, 1 papers with code

Artificial intelligence-aided protein engineering: from topological data analysis to deep protein language models

no code implementations27 Jul 2023 Yuchi Qiu, Guo-Wei Wei

Protein engineering is an emerging field in biotechnology that has the potential to revolutionize various areas, such as antibody design, drug discovery, food security, ecology, and more.

Drug Discovery Protein Structure Prediction +1

Mathematics-assisted directed evolution and protein engineering

no code implementations6 Jun 2023 Yuchi Qiu, Guo-Wei Wei

Persistent Laplacians, an emerging technique in topological data analysis (TDA), have made structure-based embeddings a superb option in AIDE and AIPE.

Topological Data Analysis

SVSBI: Sequence-based virtual screening of biomolecular interactions

1 code implementation27 Dec 2022 Li Shen, Hongsong Feng, Yuchi Qiu, Guo-Wei Wei

Virtual screening (VS) is an essential technique for understanding biomolecular interactions, particularly, drug design and discovery.

Drug Discovery Molecular Docking

Emerging dominant SARS-CoV-2 variants

no code implementations18 Oct 2022 Jiahui Chen, Rui Wang, Yuta Hozumi, Gengzhuo Liu, Yuchi Qiu, Xiaoqi Wei, Guo-Wei Wei

Accurate and reliable forecasting of emerging dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants enables policymakers and vaccine makers to get prepared for future waves of infections.

Persistent Laplacian projected Omicron BA.4 and BA.5 to become new dominating variants

no code implementations1 May 2022 Jiahui Chen, Yuchi Qiu, Rui Wang, Guo-Wei Wei

In particular, BA. 4 and BA. 5 are about 36\% more infectious than BA. 2 and are projected to become new dominating variants by natural selection.

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

no code implementations1 Feb 2021 Kaifu Gao, Rui Wang, Jiahui Chen, Limei Cheng, Jaclyn Frishcosy, Yuta Huzumi, Yuchi Qiu, Tom Schluckbier, Guo-Wei Wei

To provide the reader a quick update about the status of molecular modeling, simulation, and prediction of SARS-CoV-2, we present a comprehensive and systematic methodology-centered narrative in the nick of time.

Drug Discovery

Noise control and utility: from regulatory network to spatial patterning

no code implementations19 Jan 2020 Qing Nie, Lingxia Qiao, Yuchi Qiu, Lei Zhang, Wei Zhao

Stochasticity (or noise) at cellular and molecular levels has been observed extensively as a universal feature for living systems.

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