no code implementations • 7 Jan 2023 • Fabian A. Braeu, Thanadet Chuangsuwanich, Tin A. Tun, Shamira A. Perera, Rahat Husain, Aiste Kadziauskiene, Leopold Schmetterer, Alexandre H. Thiéry, George Barbastathis, Tin Aung, Michaël J. A. Girard
In both approaches, we observed that structural changes were more prominent in the superior and inferior quadrant of the ONH, particularly in the RNFL, the prelamina, and the LC.
no code implementations • 9 Jun 2022 • Fabian A. Braeu, Thanadet Chuangsuwanich, Tin A. Tun, Alexandre H. Thiery, Tin Aung, George Barbastathis, Michaël J. A. Girard
$\mathbf{Conclusions}$: We propose an AI-driven approach that can assess the robustness of a given ONH solely from a single OCT scan of the ONH, and without the need to perform biomechanical testing.
no code implementations • 14 Apr 2022 • Alexandre H. Thiery, Fabian Braeu, Tin A. Tun, Tin Aung, Michael J. A. Girard
Discussion: We provide a proof-of-principle for the application of geometric deep learning in the field of glaucoma.
no code implementations • 14 Apr 2022 • Fabian A. Braeu, Alexandre H. Thiéry, Tin A. Tun, Aiste Kadziauskiene, George Barbastathis, Tin Aung, Michaël J. A. Girard
To this end, we aimed: (1) To compare the performance of two relatively recent geometric deep learning techniques in diagnosing glaucoma from a single OCT scan of the ONH; and (2) To identify the 3D structural features of the ONH that are critical for the diagnosis of glaucoma.
no code implementations • 7 Nov 2021 • Satish K. Panda, Haris Cheong, Tin A. Tun, Thanadet Chuangsuwanich, Aiste Kadziauskiene, Vijayalakshmi Senthil, Ramaswami Krishnadas, Martin L. Buist, Shamira Perera, Ching-Yu Cheng, Tin Aung, Alexandre H. Thiery, Michael J. A. Girard
Our work also suggested that the major retinal blood vessels form a skeleton -- the configuration of which may be representative of major ONH structural changes as typically observed with the development and progression of glaucoma.
no code implementations • 17 Dec 2020 • Satish K. Panda, Haris Cheong, Tin A. Tun, Sripad K. Devella, Ramaswami Krishnadas, Martin L. Buist, Shamira Perera, Ching-Yu Cheng, Tin Aung, Alexandre H. Thiéry, Michaël J. A. Girard
We argue this is because the vast amount of information available in a 3D OCT scan of the ONH has not been fully exploited.
no code implementations • 6 Oct 2020 • Haris Cheong, Sripad Krishna Devalla, Thanadet Chuangsuwanich, Tin A. Tun, Xiaofei Wang, Tin Aung, Leopold Schmetterer, Martin L. Buist, Craig Boote, Alexandre H. Thiéry, Michaël J. A. Girard
Speckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians.
no code implementations • 22 Feb 2020 • Sripad Krishna Devalla, Tan Hung Pham, Satish Kumar Panda, Liang Zhang, Giridhar Subramanian, Anirudh Swaminathan, Chin Zhi Yun, Mohan Rajan, Sujatha Mohan, Ramaswami Krishnadas, Vijayalakshmi Senthil, John Mark S. de Leon, Tin A. Tun, Ching-Yu Cheng, Leopold Schmetterer, Shamira Perera, Tin Aung, Alexandre H. Thiery, Michael J. A. Girard
Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma.
no code implementations • 10 Feb 2019 • Huazhu Fu, Yanwu Xu, Stephen Lin, Damon Wing Kee Wong, Mani Baskaran, Meenakshi Mahesh, Tin Aung, Jiang Liu
A Multi-Level Deep Network (MLDN) is proposed to formulate this learning, which utilizes three particular AS-OCT regions based on clinical priors: the global anterior segment structure, local iris region, and anterior chamber angle (ACA) patch.
no code implementations • 27 Sep 2018 • Sripad Krishna Devalla, Giridhar Subramanian, Tan Hung Pham, Xiaofei Wang, Shamira Perera, Tin A. Tun, Tin Aung, Leopold Schmetterer, Alexandre H. Thiery, Michael J. A. Girard
For all the ONH tissues, the mean CNR increased from $3. 50 \pm 0. 56$ (single-frame) to $7. 63 \pm 1. 81$ (denoised).
no code implementations • 10 Sep 2018 • Huazhu Fu, Yanwu Xu, Stephen Lin, Damon Wing Kee Wong, Baskaran Mani, Meenakshi Mahesh, Tin Aung, Jiang Liu
A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT).
no code implementations • 1 Mar 2018 • Sripad Krishna Devalla, Prajwal K. Renukanand, Bharathwaj K. Sreedhar, Shamira Perera, Jean-Martial Mari, Khai Sing Chin, Tin A. Tun, Nicholas G. Strouthidis, Tin Aung, Alexandre H. Thiery, Michael J. A. Girard
Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology.
no code implementations • 24 Jul 2017 • Sripad Krishna Devalla, Jean-Martial Mari, Tin A. Tun, Nicholas G. Strouthidis, Tin Aung, Alexandre H. Thiery, Michael J. A. Girard
Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH).