Search Results for author: Renaud Dessalles

Found 3 papers, 0 papers with code

How heterogeneous thymic output and homeostatic proliferation shape naive T cell receptor clone abundance distributions

no code implementations18 Jun 2019 Renaud Dessalles, Yunbei Pan, Mingtao Xia, Davide Maestrini, Maria R. D'Orsogna, Tom Chou

Using a mean-field approximation to the solution of a regulated birth-death-immigration model and a modification arising from sampling, we systematically quantify how TCR-dependent heterogeneities in immigration and proliferation rates affect the shape of clone abundance distributions (the number of different clones that are represented by a specific number of cells, or "clone counts").

Models of protein production along the cell cycle: an investigation of possible sources of noise

no code implementations17 Nov 2017 Renaud Dessalles, Vincent Fromion, Philippe Robert

In this article, we quantitatively study, through stochastic models, the efects of several intracellular phenomena, such as cell volume growth, cell division, gene replication as well as fuctuations of available RNA polymerases and ribosomes.

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