Search Results for author: Peter A. N. Bosman

Found 38 papers, 11 papers with code

Hyperparameter-Free Medical Image Synthesis for Sharing Data and Improving Site-Specific Segmentation

2 code implementations9 Apr 2024 Alexander Chebykin, Peter A. N. Bosman, Tanja Alderliesten

Sharing synthetic medical images is a promising alternative to sharing real images that can improve patient privacy and data security.

Image Generation

Stitching for Neuroevolution: Recombining Deep Neural Networks without Breaking Them

no code implementations21 Mar 2024 Arthur Guijt, Dirk Thierens, Tanja Alderliesten, Peter A. N. Bosman

To correct for differing feature representations between these layers we employ stitching, which merges the networks by introducing new layers at crossover points.

Transfer Learning

Multi-Objective Learning for Deformable Image Registration

no code implementations23 Feb 2024 Monika Grewal, Henrike Westerveld, Peter A. N. Bosman, Tanja Alderliesten

The experiments also show that the proposed MO DIR approach provides a better spread of DIR outputs across the entire trade-off front than simply training multiple neural networks with weights for each objective sampled from a grid of possible values.

Image Registration

Learning Discretized Bayesian Networks with GOMEA

no code implementations19 Feb 2024 Damy M. F. Ha, Tanja Alderliesten, Peter A. N. Bosman

The optimal discretization, however, depends on the relations modelled between the variables.

Evolutionary Algorithms

MultiFIX: An XAI-friendly feature inducing approach to building models from multimodal data

no code implementations19 Feb 2024 Mafalda Malafaia, Thalea Schlender, Peter A. N. Bosman, Tanja Alderliesten

Furthermore, it is important to understand how each modality impacts the final prediction, especially in high-stake domains, so that these models can be used in a trustworthy and responsible manner.

Explainable artificial intelligence

Fitness-based Linkage Learning and Maximum-Clique Conditional Linkage Modelling for Gray-box Optimization with RV-GOMEA

1 code implementation16 Feb 2024 Georgios Andreadis, Tanja Alderliesten, Peter A. N. Bosman

In addition, we propose a new way to model overlapping dependencies in conditional linkage models to maximize the joint sampling of fully interdependent groups of variables.

Improving the efficiency of GP-GOMEA for higher-arity operators

no code implementations15 Feb 2024 Thalea Schlender, Mafalda Malafaia, Tanja Alderliesten, Peter A. N. Bosman

Experimental results show that both proposed search enhancements have a generally positive impact on the performance of GP-GOMEA, especially when the set of operators to choose from is large and contains higher-arity operators.

A Tournament of Transformation Models: B-Spline-based vs. Mesh-based Multi-Objective Deformable Image Registration

no code implementations30 Jan 2024 Georgios Andreadis, Joas I. Mulder, Anton Bouter, Peter A. N. Bosman, Tanja Alderliesten

Although both models have been investigated in detail, a direct comparison has not yet been made, since the models are optimized using very different optimization methods in practice.

Evolutionary Algorithms Image Registration

A Joint Python/C++ Library for Efficient yet Accessible Black-Box and Gray-Box Optimization with GOMEA

no code implementations10 May 2023 Anton Bouter, Peter A. N. Bosman

Especially in a Gray-Box Optimization (GBO) setting that allows for partial evaluations, i. e., the relatively efficient evaluation of a partial modification of a solution, GOMEA is known to excel.

The Impact of Asynchrony on Parallel Model-Based EAs

no code implementations27 Mar 2023 Arthur Guijt, Dirk Thierens, Tanja Alderliesten, Peter A. N. Bosman

Thus, if an asynchronous parallel MBEA is also affected by an evaluation time bias, this could result in learned models to be less suited to solving the problem, reducing performance.

Evolutionary Algorithms

Convolutions, Transformers, and their Ensembles for the Segmentation of Organs at Risk in Radiation Treatment of Cervical Cancer

no code implementations20 Mar 2023 Vangelis Kostoulas, Peter A. N. Bosman, Tanja Alderliesten

The results show that small improvements in metrics can be achieved by advancing and merging architectures, but the predictions of the models are quite similar (most models achieve on average more than 0. 8 Dice Coefficient when compared to the outputs of other models).

MOREA: a GPU-accelerated Evolutionary Algorithm for Multi-Objective Deformable Registration of 3D Medical Images

no code implementations8 Mar 2023 Georgios Andreadis, Peter A. N. Bosman, Tanja Alderliesten

A recent multi-objective approach that uses the Multi-Objective Real-Valued Gene-pool Optimal Mixing Evolutionary Algorithm (MO-RV-GOMEA) and a dual-dynamic mesh transformation model has shown promise, exposing the trade-offs inherent to image registration problems and modeling large deformations in 2D.

Image Registration

Clinically Acceptable Segmentation of Organs at Risk in Cervical Cancer Radiation Treatment from Clinically Available Annotations

no code implementations21 Feb 2023 Monika Grewal, Dustin van Weersel, Henrike Westerveld, Peter A. N. Bosman, Tanja Alderliesten

Following this motivation, we present an approach to learn a deep learning model for the automatic segmentation of Organs at Risk (OARs) in cervical cancer radiation treatment from a large clinically available dataset of Computed Tomography (CT) scans containing data inhomogeneity, label noise, and missing annotations.

Computed Tomography (CT) Imputation +1

Coefficient Mutation in the Gene-pool Optimal Mixing Evolutionary Algorithm for Symbolic Regression

no code implementations26 Apr 2022 Marco Virgolin, Peter A. N. Bosman

We find that coefficient mutation can help re-discovering the underlying equation by a substantial amount, but only when no noise is added to the target variable.

regression Symbolic Regression

Obtaining Smoothly Navigable Approximation Sets in Bi-Objective Multi-Modal Optimization

no code implementations17 Mar 2022 Renzo J. Scholman, Anton Bouter, Leah R. M. Dickhoff, Tanja Alderliesten, Peter A. N. Bosman

Even if a Multi-modal Multi-Objective Evolutionary Algorithm (MMOEA) is designed to find solutions well spread over all locally optimal approximation sets of a Multi-modal Multi-objective Optimization Problem (MMOP), there is a risk that the found set of solutions is not smoothly navigable because the solutions belong to various niches, reducing the insight for decision makers.

Adaptive Objective Configuration in Bi-Objective Evolutionary Optimization for Cervical Cancer Brachytherapy Treatment Planning

no code implementations16 Mar 2022 Leah R. M. Dickhoff, Ellen M. Kerkhof, Heloisa H. Deuzeman, Carien L. Creutzberg, Tanja Alderliesten, Peter A. N. Bosman

For this reason, we propose a novel adaptive objective configuration method to use with MO-RV-GOMEA so that we can accommodate additional aims of this nature.

Solving Multi-Structured Problems by Introducing Linkage Kernels into GOMEA

1 code implementation11 Mar 2022 Arthur Guijt, Dirk Thierens, Tanja Alderliesten, Peter A. N. Bosman

This cannot be modelled sufficiently well when using linkage models that aim at capturing a single type of linkage structure, deteriorating the advantages brought by MBEAs.

Evolutionary Algorithms

Evolutionary Neural Cascade Search across Supernetworks

1 code implementation8 Mar 2022 Alexander Chebykin, Tanja Alderliesten, Peter A. N. Bosman

A recent method called Neural Architecture Transfer (NAT) further improves the efficiency of NAS for computer vision tasks by using a multi-objective evolutionary algorithm to find high-quality subnetworks of a supernetwork pretrained on ImageNet.

Neural Architecture Search

Data variation-aware medical image segmentation

no code implementations24 Feb 2022 Arkadiy Dushatskiy, Gerry Lowe, Peter A. N. Bosman, Tanja Alderliesten

In experiments with a real clinical dataset of CT scans with prostate segmentations, our approach provides an improvement of several percentage points in terms of Dice and surface Dice coefficients compared to when all network paths are trained on all training data.

Image Segmentation Medical Image Segmentation +2

Multi-Objective Dual Simplex-Mesh Based Deformable Image Registration for 3D Medical Images -- Proof of Concept

no code implementations22 Feb 2022 Georgios Andreadis, Peter A. N. Bosman, Tanja Alderliesten

Concordantly, this work introduces the first method for multi-objective 3D deformable image registration, using a 3D dual-dynamic grid transformation model based on simplex meshes while still supporting the incorporation of annotated guidance information and multi-resolution schemes.

Image Registration

Adults as Augmentations for Children in Facial Emotion Recognition with Contrastive Learning

no code implementations10 Feb 2022 Marco Virgolin, Andrea De Lorenzo, Tanja Alderliesten, Peter A. N. Bosman

Our results indicate that adult data can be considered to be a meaningful augmentation of pediatric data for the recognition of emotional facial expression in children, and open up the possibility for other applications of contrastive learning to improve pediatric care by complementing data of children with that of adults.

Contrastive Learning Data Augmentation +1

Heed the Noise in Performance Evaluations in Neural Architecture Search

no code implementations4 Feb 2022 Arkadiy Dushatskiy, Tanja Alderliesten, Peter A. N. Bosman

Due to stochastic factors in neural network initialization, training, and the chosen train/validation dataset split, the performance evaluation of a neural network architecture, which is often based on a single learning run, is also stochastic.

Combinatorial Optimization Evolutionary Algorithms +4

Parameterless Gene-pool Optimal Mixing Evolutionary Algorithms

no code implementations11 Sep 2021 Arkadiy Dushatskiy, Marco Virgolin, Anton Bouter, Dirk Thierens, Peter A. N. Bosman

When it comes to solving optimization problems with evolutionary algorithms (EAs) in a reliable and scalable manner, detecting and exploiting linkage information, i. e., dependencies between variables, can be key.

Evolutionary Algorithms Management

Multi-Objective Learning to Predict Pareto Fronts Using Hypervolume Maximization

1 code implementation8 Feb 2021 Timo M. Deist, Monika Grewal, Frank J. W. M. Dankers, Tanja Alderliesten, Peter A. N. Bosman

We discuss and illustrate why training processes to approximate Pareto fronts need to optimize on fronts of individual training samples instead of on only the front of average losses.

Multi-objective Optimization by Uncrowded Hypervolume Gradient Ascent

3 code implementations9 Jul 2020 Timo M. Deist, Stefanus C. Maree, Tanja Alderliesten, Peter A. N. Bosman

On several bi-objective benchmarks, we find that gradient-based algorithms outperform the tested EAs by obtaining a better hypervolume with fewer evaluations whenever exact gradients of the multiple objective functions are available and in case of small evaluation budgets.

Optimization and Control

An End-to-end Deep Learning Approach for Landmark Detection and Matching in Medical Images

2 code implementations21 Jan 2020 Monika Grewal, Timo M. Deist, Jan Wiersma, Peter A. N. Bosman, Tanja Alderliesten

We tested the approach on 22, 206 pairs of 2D slices with varying levels of intensity, affine, and elastic transformations.

Computed Tomography (CT)

Machine learning for automatic construction of pseudo-realistic pediatric abdominal phantoms

no code implementations9 Sep 2019 Marco Virgolin, Ziyuan Wang, Tanja Alderliesten, Peter A. N. Bosman

To assess the effects of radiation therapy, treatment plans are typically simulated on phantoms, i. e., virtual surrogates of patient anatomy.

Anatomy BIG-bench Machine Learning +1

On Explaining Machine Learning Models by Evolving Crucial and Compact Features

no code implementations4 Jul 2019 Marco Virgolin, Tanja Alderliesten, Peter A. N. Bosman

In this article, we assess to what extent GP still performs favorably at feature construction when constructing features that are (1) Of small-enough number, to enable visualization of the behavior of the ML model; (2) Of small-enough size, to enable interpretability of the features themselves; (3) Of sufficient informative power, to retain or even improve the performance of the ML algorithm.

BIG-bench Machine Learning

Improving Model-based Genetic Programming for Symbolic Regression of Small Expressions

1 code implementation3 Apr 2019 Marco Virgolin, Tanja Alderliesten, Cees Witteveen, Peter A. N. Bosman

We show that the non-uniformity in the distribution of the genotype in GP populations negatively biases LL, and propose a method to correct for this.

regression Symbolic Regression

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