no code implementations • 24 Apr 2024 • Saeed Mahdisoltani, Pranav Murugan, Arup K Chakraborty, Mehran Kardar
A persistent public health challenge is finding immunization schemes that are effective in combating highly mutable pathogens such as HIV and influenza viruses.
no code implementations • 17 Oct 2023 • Federica Ferretti, Mehran Kardar
We describe the evolution of the B cell population via a quasispecies dynamics, with species corresponding to unique B cell receptors (BCRs), where the desired multi-scale structure is reflected on the mutational connectivity of the accessible BCR space, and on the statistical properties of its fitness landscape.
no code implementations • 18 Jan 2023 • Daniel W. Swartz, Hyunseok Lee, Mehran Kardar, Kirill S. Korolev
In growing populations, the fate of mutations depends on their competitive ability against the ancestor and their ability to colonize new territory.
no code implementations • 23 Aug 2021 • Daniel Swartz, Bertrand Ottino-Löffler, Mehran Kardar
First proposed as an empirical rule over half a century ago, the Richards growth equation has been frequently invoked in population modeling and pandemic forecasting.
no code implementations • 23 Dec 2020 • David Gelbwaser-Klimovsky, Noah Graham, Mehran Kardar, Matthias Krüger
In the near field regime, this velocity can be reduced to the order of $\bar\omega d \eta_c$, where $\bar\omega$ is a typical material frequency.
Quantum Physics
