no code implementations • 11 Jan 2024 • Lucas W. Remedios, Shunxing Bao, Samuel W. Remedios, Ho Hin Lee, Leon Y. Cai, Thomas Li, Ruining Deng, Can Cui, Jia Li, Qi Liu, Ken S. Lau, Joseph T. Roland, Mary K. Washington, Lori A. Coburn, Keith T. Wilson, Yuankai Huo, Bennett A. Landman
In this paper, we propose to use inter-modality learning to label previously un-labelable cell types on virtual H&E.
no code implementations • 9 Jan 2024 • Hanliang Xu, Nancy R. Newlin, Michael E. Kim, Chenyu Gao, Praitayini Kanakaraj, Aravind R. Krishnan, Lucas W. Remedios, Nazirah Mohd Khairi, Kimberly Pechman, Derek Archer, Timothy J. Hohman, Angela L. Jefferson, The BIOCARD Study Team, Ivana Isgum, Yuankai Huo, Daniel Moyer, Kurt G. Schilling, Bennett A. Landman
First, we plotted the graph measures and used coefficient of variation (CoV) and the Mann-Whitney U test to evaluate different methods' effectiveness in removing site effects on the matrices and the derived graph measures.
no code implementations • 22 Sep 2023 • Aravind R. Krishnan, Kaiwen Xu, Thomas Li, Chenyu Gao, Lucas W. Remedios, Praitayini Kanakaraj, Ho Hin Lee, Shunxing Bao, Kim L. Sandler, Fabien Maldonado, Ivana Isgum, Bennett A. Landman
In this study, we adopt an unpaired image translation approach to investigate harmonization between and across reconstruction kernels from different manufacturers by constructing a multipath cycle generative adversarial network (GAN).
no code implementations • 20 Aug 2023 • Shunxing Bao, Sichen Zhu, Vasantha L Kolachala, Lucas W. Remedios, Yeonjoo Hwang, Yutong Sun, Ruining Deng, Can Cui, Yike Li, Jia Li, Joseph T. Roland, Qi Liu, Ken S. Lau, Subra Kugathasan, Peng Qiu, Keith T. Wilson, Lori A. Coburn, Bennett A. Landman, Yuankai Huo
This analysis is based on data collected at the two research institutes.
no code implementations • 3 Jul 2023 • Can Cui, Yaohong Wang, Shunxing Bao, Yucheng Tang, Ruining Deng, Lucas W. Remedios, Zuhayr Asad, Joseph T. Roland, Ken S. Lau, Qi Liu, Lori A. Coburn, Keith T. Wilson, Bennett A. Landman, Yuankai Huo
Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training.
no code implementations • 1 Jul 2023 • Can Cui, Ruining Deng, Quan Liu, Tianyuan Yao, Shunxing Bao, Lucas W. Remedios, Yucheng Tang, Yuankai Huo
The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach.
1 code implementation • 31 May 2023 • Ruining Deng, Yanwei Li, Peize Li, Jiacheng Wang, Lucas W. Remedios, Saydolimkhon Agzamkhodjaev, Zuhayr Asad, Quan Liu, Can Cui, Yaohong Wang, Yihan Wang, Yucheng Tang, Haichun Yang, Yuankai Huo
The contribution of this paper is threefold: (1) We proposed a molecular-empowered learning scheme for multi-class cell segmentation using partial labels from lay annotators; (2) The proposed method integrated Giga-pixel level molecular-morphology cross-modality registration, molecular-informed annotation, and molecular-oriented segmentation model, so as to achieve significantly superior performance via 3 lay annotators as compared with 2 experienced pathologists; (3) A deep corrective learning (learning with imperfect label) method is proposed to further improve the segmentation performance using partially annotated noisy data.
no code implementations • 24 Apr 2023 • Lucas W. Remedios, Leon Y. Cai, Samuel W. Remedios, Karthik Ramadass, Aravind Krishnan, Ruining Deng, Can Cui, Shunxing Bao, Lori A. Coburn, Yuankai Huo, Bennett A. Landman
The M1 Ultra SoC was able to train the model directly on gigapixel images (16000$\times$64000 pixels, 1. 024 billion pixels) with a batch size of 1 using over 100 GB of unified memory for the process at an average speed of 1 minute and 21 seconds per batch with Tensorflow 2/Keras.
no code implementations • 9 Apr 2023 • Ruining Deng, Can Cui, Quan Liu, Tianyuan Yao, Lucas W. Remedios, Shunxing Bao, Bennett A. Landman, Lee E. Wheless, Lori A. Coburn, Keith T. Wilson, Yaohong Wang, Shilin Zhao, Agnes B. Fogo, Haichun Yang, Yucheng Tang, Yuankai Huo
However, it does not consistently achieve satisfying performance for dense instance object segmentation, even with 20 prompts (clicks/boxes) on each image.
1 code implementation • 1 Apr 2023 • Ruining Deng, Can Cui, Lucas W. Remedios, Shunxing Bao, R. Michael Womick, Sophie Chiron, Jia Li, Joseph T. Roland, Ken S. Lau, Qi Liu, Keith T. Wilson, Yaohong Wang, Lori A. Coburn, Bennett A. Landman, Yuankai Huo
Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology.
1 code implementation • 15 Aug 2022 • Ruining Deng, Can Cui, Lucas W. Remedios, Shunxing Bao, R. Michael Womick, Sophie Chiron, Jia Li, Joseph T. Roland, Ken S. Lau, Qi Liu, Keith T. Wilson, Yaohong Wang, Lori A. Coburn, Bennett A. Landman, Yuankai Huo
Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations.
no code implementations • 3 Jun 2021 • Ho Hin Lee, Yucheng Tang, Qi Yang, Xin Yu, Shunxing Bao, Leon Y. Cai, Lucas W. Remedios, Bennett A. Landman, Yuankai Huo
Medical image segmentation, or computing voxelwise semantic masks, is a fundamental yet challenging task to compute a voxel-level semantic mask.