Search Results for author: Lucas Böttcher

Found 14 papers, 13 papers with code

Control of Medical Digital Twins with Artificial Neural Networks

1 code implementation18 Mar 2024 Lucas Böttcher, Luis L. Fonseca, Reinhard C. Laubenbacher

A key technology for this purpose involves medical digital twins, computational models of human biology that can be personalized and dynamically updated to incorporate patient-specific data collected over time.

Metamodeling and Control of Medical Digital Twins

1 code implementation8 Feb 2024 Luis L. Fonseca, Lucas Böttcher, Borna Mehrad, Reinhard C. Laubenbacher

Medical digital twins, computational models that integrate a wide range of health-related data about a person and can be dynamically updated, are a key technology that can help guide medical decisions.

Gradient-free training of neural ODEs for system identification and control using ensemble Kalman inversion

1 code implementation15 Jul 2023 Lucas Böttcher

Ensemble Kalman inversion (EKI) is a sequential Monte Carlo method used to solve inverse problems within a Bayesian framework.

Visualizing high-dimensional loss landscapes with Hessian directions

1 code implementation28 Aug 2022 Lucas Böttcher, Gregory Wheeler

We show that saddle points in the original space are rarely correctly identified as such in expected lower-dimensional representations if random projections are used.

Vocal Bursts Intensity Prediction

Near-optimal control of dynamical systems with neural ordinary differential equations

1 code implementation22 Jun 2022 Lucas Böttcher, Thomas Asikis

Optimal control problems naturally arise in many scientific applications where one wishes to steer a dynamical system from a certain initial state $\mathbf{x}_0$ to a desired target state $\mathbf{x}^*$ in finite time $T$.

Hyperparameter Optimization

Mathematical Characterization of Private and Public Immune Repertoire Sequences

1 code implementation18 May 2022 Lucas Böttcher, Sascha Wald, Tom Chou

Complementing the results on simulated repertoires, we derive explicit expressions for the richness and its uncertainty for specific, single-parameter truncated power-law probability distributions.

Spectrally Adapted Physics-Informed Neural Networks for Solving Unbounded Domain Problems

1 code implementation6 Feb 2022 Mingtao Xia, Lucas Böttcher, Tom Chou

We propose a solution to such problems by combining two classes of numerical methods: (i) adaptive spectral methods and (ii) physics-informed neural networks (PINNs).

Control of Dual-Sourcing Inventory Systems using Recurrent Neural Networks

1 code implementation16 Jan 2022 Lucas Böttcher, Thomas Asikis, Ioannis Fragkos

To solve such optimization problems, inventory managers need to decide what quantities to order from each supplier, given the net inventory and outstanding orders, so that the expected backlogging, holding, and sourcing costs are jointly minimized.

Management

Implicit energy regularization of neural ordinary-differential-equation control

no code implementations11 Mar 2021 Lucas Böttcher, Nino Antulov-Fantulin, Thomas Asikis

Although optimal control problems of dynamical systems can be formulated within the framework of variational calculus, their solution for complex systems is often analytically and computationally intractable.

Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities

1 code implementation10 Jan 2021 Lucas Böttcher, Maria D'Orsogna, Tom Chou

We find that the average excess death across the entire US is 13$\%$ higher than the number of reported COVID-19 deaths.

From classical to quantum walks with stochastic resetting on networks

1 code implementation2 Aug 2020 Sascha Wald, Lucas Böttcher

We study the influence of quantum effects on the stationary and long-time average probability distribution by interpolating between the classical and quantum regime.

Statistical Mechanics Quantum Physics

Neural Ordinary Differential Equation Control of Dynamics on Graphs

1 code implementation17 Jun 2020 Thomas Asikis, Lucas Böttcher, Nino Antulov-Fantulin

We study the ability of neural networks to calculate feedback control signals that steer trajectories of continuous time non-linear dynamical systems on graphs, which we represent with neural ordinary differential equations (neural ODEs).

Reinforcement Learning (RL)

Learning the Ising Model with Generative Neural Networks

1 code implementation15 Jan 2020 Francesco D'Angelo, Lucas Böttcher

We also find that convolutional layers in VAEs are important to model spin correlations whereas RBMs achieve similar or even better performances without convolutional filters.

Representation Learning

Cannot find the paper you are looking for? You can Submit a new open access paper.