Search Results for author: Yikun Zhang

Found 7 papers, 5 papers with code

Atomas: Hierarchical Alignment on Molecule-Text for Unified Molecule Understanding and Generation

no code implementations23 Apr 2024 Yikun Zhang, Geyan Ye, Chaohao Yuan, Bo Han, Long-Kai Huang, Jianhua Yao, Wei Liu, Yu Rong

We design a Hierarchical Adaptive Alignment model to concurrently learn the fine-grained fragment correspondence between two modalities and align these representations of fragments in three levels.

Drug Discovery molecular representation +2

Functional Protein Design with Local Domain Alignment

no code implementations18 Apr 2024 Chaohao Yuan, Songyou Li, Geyan Ye, Yikun Zhang, Long-Kai Huang, Wenbing Huang, Wei Liu, Jianhua Yao, Yu Rong

The core challenge of de novo protein design lies in creating proteins with specific functions or properties, guided by certain conditions.

Protein Annotation Protein Design

Mode and Ridge Estimation in Euclidean and Directional Product Spaces: A Mean Shift Approach

1 code implementation16 Oct 2021 Yikun Zhang, Yen-Chi Chen

The set of local modes and the ridge lines estimated from a dataset are important summary characteristics of the data-generating distribution.

Linear Convergence of the Subspace Constrained Mean Shift Algorithm: From Euclidean to Directional Data

2 code implementations29 Apr 2021 Yikun Zhang, Yen-Chi Chen

This paper studies the linear convergence of the subspace constrained mean shift (SCMS) algorithm, a well-known algorithm for identifying a density ridge defined by a kernel density estimator.

The EM Perspective of Directional Mean Shift Algorithm

1 code implementation25 Jan 2021 Yikun Zhang, Yen-Chi Chen

Under the (generalized) EM framework, we provide a new proof for the ascending property of density estimates and demonstrate the global convergence of directional mean shift sequences.

Kernel Smoothing, Mean Shift, and Their Learning Theory with Directional Data

1 code implementation23 Oct 2020 Yikun Zhang, Yen-Chi Chen

Directional data consist of observations distributed on a (hyper)sphere, and appear in many applied fields, such as astronomy, ecology, and environmental science.

Astronomy Clustering +1

Iterative Reconstruction for Low-Dose CT using Deep Gradient Priors of Generative Model

5 code implementations27 Sep 2020 Zhuonan He, Yikun Zhang, Yu Guan, Shanzhou Niu, Yi Zhang, Yang Chen, Qiegen Liu

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications.

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