Search Results for author: Xinghua Lu

Found 8 papers, 5 papers with code

Understanding Heart-Failure Patients EHR Clinical Features via SHAP Interpretation of Tree-Based Machine Learning Model Predictions

1 code implementation20 Mar 2021 Shuyu Lu, Ruoyu Chen, Wei Wei, Xinghua Lu

We examined whether machine learning models, more specifically the XGBoost model, can accurately predict patient stage based on EHR, and we further applied the SHapley Additive exPlanations (SHAP) framework to identify informative features and their interpretations.

Learning Latent Causal Structures with a Redundant Input Neural Network

no code implementations29 Mar 2020 Jonathan D. Young, Bryan Andrews, Gregory F. Cooper, Xinghua Lu

We developed a deep learning model, which we call a redundant input neural network (RINN), with a modified architecture and a regularized objective function to find causal relationships between input, hidden, and output variables.

Causal Discovery

Supervised Vector Quantized Variational Autoencoder for Learning Interpretable Global Representations

1 code implementation24 Sep 2019 Yifan Xue, Michael Ding, Xinghua Lu

When training a deep generative model, the observed data are often associated with certain categorical labels, and, in parallel with learning to regenerate data and simulate new data, learning an interpretable representation of each class of data is also a process of acquiring knowledge.

Probing Biomedical Embeddings from Language Models

1 code implementation WS 2019 Qiao Jin, Bhuwan Dhingra, William W. Cohen, Xinghua Lu

For this we use the pre-trained LMs as fixed feature extractors and restrict the downstream task models to not have additional sequence modeling layers.

NER Word Embeddings

From genome to phenome: Predicting multiple cancer phenotypes based on somatic genomic alterations via the genomic impact transformer

1 code implementation31 Jan 2019 Yifeng Tao, Chunhui Cai, William Cohen, Xinghua Lu

Here, we present a deep neural network model with encoder-decoder architecture, referred to as genomic impact transformer (GIT), to infer the functional impact of SGAs on cellular signaling systems through modeling the statistical relationships between SGA events and differentially expressed genes (DEGs) in tumors.

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