Search Results for author: Won Chang

Found 4 papers, 1 papers with code

Statistical Power Analysis for Designing Bulk, Single-Cell, and Spatial Transcriptomics Experiments: Review, Tutorial, and Perspectives

no code implementations7 Jan 2023 Hyeongseon Jeon, Juan Xie, Yeseul Jeon, Kyeong Joo Jung, Arkobrato Gupta, Won Chang, Dongjun Chung

In this paper, we review and discuss the power analysis for three types of gene expression profiling technologies from a practical standpoint, including bulk RNA-seq, single-cell RNA-seq, and high-throughput spatial transcriptomics.

graph-GPA 2.0: A Graphical Model for Multi-disease Analysis of GWAS Results with Integration of Functional Annotation Data

no code implementations14 Apr 2022 Qiaolan Deng, Jin Hyun Nam, Ayse Selen Yilmaz, Won Chang, Maciej Pietrzak, Lang Li, Hang J. Kim, Dongjun Chung

These results demonstrate that GGPA 2. 0 can be a powerful tool to identify associated variants associated with each phenotype or those shared across multiple phenotypes, while also promoting understanding of functional mechanisms underlying the associated variants.

Literature Mining

Fast and accurate learned multiresolution dynamical downscaling for precipitation

1 code implementation18 Jan 2021 Jiali Wang, Zhengchun Liu, Ian Foster, Won Chang, Rajkumar Kettimuthu, Rao Kotamarthi

We compare the four new CNN-derived high-resolution precipitation results with precipitation generated from original high resolution simulations, a bilinear interpolater and the state-of-the-art CNN-based super-resolution (SR) technique.

Generative Adversarial Network Super-Resolution

Computer Model Calibration with Time Series Data using Deep Learning and Quantile Regression

no code implementations29 Aug 2020 Saumya Bhatnagar, Won Chang, Seonjin Kim Jiali Wang

The existing standard calibration framework suffers from inferential issues when the model output and observational data are high-dimensional dependent data such as large time series due to the difficulty in building an emulator and the non-identifiability between effects from input parameters and data-model discrepancy.

regression Time Series +1

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