DiscDiff: Latent Diffusion Model for DNA Sequence Generation

no code implementations • 8 Feb 2024 • Zehui Li, Yuhao Ni, William A V Beardall, Guoxuan Xia, Akashaditya Das, Guy-Bart Stan, Yiren Zhao

This paper introduces a novel framework for DNA sequence generation, comprising two key components: DiscDiff, a Latent Diffusion Model (LDM) tailored for generating discrete DNA sequences, and Absorb-Escape, a post-training algorithm designed to refine these sequences.

Genomic Interpreter: A Hierarchical Genomic Deep Neural Network with 1D Shifted Window Transformer

1 code implementation • 8 Jun 2023 • Zehui Li, Akashaditya Das, William A V Beardall, Yiren Zhao, Guy-Bart Stan

This work presents Genomic Interpreter: a novel architecture for genomic assay prediction.

Interpretable Machine Learning