no code implementations • 21 Jul 2021 • Tim Hahn, Hamidreza Jamalabadi, Daniel Emden, Janik Goltermann, Jan Ernsting, Nils R. Winter, Lukas Fisch, Ramona Leenings, Kelvin Sarink, Vincent Holstein, Marius Gruber, Dominik Grotegerd, Susanne Meinert, Katharina Dohm, Elisabeth J. Leehr, Maike Richter, Lisa Sindermann, Verena Enneking, Hannah Lemke, Stephanie Witt, Marcella Rietschel, Katharina Brosch, Julia-Katharina Pfarr, Tina Meller, Kai Gustav Ringwald, Simon Schmitt, Frederike Stein, Igor Nenadic, Tilo Kircher, Bertram Müller-Myhsok, Till F. M. Andlauer, Jonathan Repple, Udo Dannlowski, Nils Opel
We quantified the theoretical energy required for each patient and time-point to reach a symptom-free state given individual symptom-network topology (E 0 ) and 1) tested if E 0 predicts future symptom improvement and 2) whether this relationship is moderated by Polygenic Risk Scores (PRS) of mental disorders, childhood maltreatment experience, and self-reported resilience.