Search Results for author: Tal Einav

Found 3 papers, 0 papers with code

Using Interpretable Machine Learning to Massively Increase the Number of Antibody-Virus Interactions Across Studies

no code implementations10 Jun 2022 Tal Einav, Rong Ma

We use this framework to greatly expand seven influenza datasets utilizing hemagglutination inhibition, validating our method upon 200, 000 existing measurements and predicting 2, 000, 000 new values along with their uncertainties.

Interpretable Machine Learning

When Two are Better than One: Modeling the Mechanisms of Antibody Mixtures

no code implementations16 Oct 2019 Tal Einav, Jesse D Bloom

It is difficult to predict how antibodies will behave when mixed together, even after each has been independently characterized.

How the Avidity of Polymerase Binding to the -35/-10 Promoter Sites Affects Gene Expression

no code implementations3 Apr 2019 Tal Einav, Rob Phillips

We show that this the refined energy matrix model can characterize the full suite of gene expression data and explore several applications of this framework, namely, how multivalent binding at the -35 and -10 sites can buffer RNAP kinetics against mutations and how promoters that bind overly tightly to RNA polymerase can inhibit gene expression.

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