no code implementations • 28 Mar 2023 • Giovanna Maria Dimitri, Simeon Spasov, Andrea Duggento, Luca Passamonti, Pietro Li`o, Nicola Toschi
As proof of concept, we test our architecture on the well characterized Human Connectome Project database demonstrating that our latent embeddings can be clustered into easily separable subject strata which, in turn, map to different phenotypical information which was not included in the embedding creation process.
no code implementations • 26 Jan 2023 • Alexander Campbell, Simeon Spasov, Nicola Toschi, Pietro Lio
In this paper, we propose a dynamic brain graph deep generative model (DBGDGM) which simultaneously clusters brain regions into temporally evolving communities and learns dynamic unsupervised node embeddings.
1 code implementation • 25 Sep 2022 • Matteo Ferrante, Tommaso Boccato, Simeon Spasov, Andrea Duggento, Nicola Toschi
Then, we reconstruct the sample based on a similarity measure between the sample embedding and the prototypical vectors of the clusters.
no code implementations • 24 Sep 2022 • Matteo Ferrante, Tommaso Boccato, Simeon Spasov, Andrea Duggento, Nicola Toschi
The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a precision medicine paradigm, where in principle dense patient-specific data can be employed to formulate individual predictions and/or stratify patients into finer-grained groups which may follow more homogeneous trajectories and therefore empower clinical trials.
no code implementations • 16 Jul 2020 • Simeon Spasov, Alessandro Di Stefano, Pietro Lio, Jian Tang
At each time step link generation is performed by first assigning node membership from a distribution over the communities, and then sampling a neighbor from a distribution over the nodes for the assigned community.
no code implementations • 8 Jul 2020 • Samuel Glass, Simeon Spasov, Pietro Liò
A novel method to identify salient computational paths within randomly wired neural networks before training is proposed.
1 code implementation • 13 Sep 2019 • Devin Taylor, Simeon Spasov, Pietro Liò
Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and epidemiological models.