Search Results for author: Sergey Koren

Found 3 papers, 1 papers with code

Graph-based variant discovery reveals novel dynamics in the human microbiome

no code implementations3 Mar 2024 Harihara Subrahmaniam Muralidharan, Jacquelyn S Michaelis, Jay Ghurye, Todd Treangen, Sergey Koren, Marcus Fedarko, Mihai Pop

Sequence differences between the strains of bacteria comprising host-associated and environmental microbiota may play a role in community assembly and influence the resilience of microbial communities to disturbances.

MetaCompass: Reference-guided Assembly of Metagenomes

no code implementations3 Mar 2024 Tu Luan, Victoria Cepeda, Bo Liu, Zac Bowen, Ujjwal Ayyangar, Mathieu Almeida, Christopher M. Hill, Sergey Koren, Todd J. Treangen, Adam Porter, Mihai Pop

Metagenomic studies have primarily relied on de novo assembly for reconstructing genes and genomes from microbial mixtures.

Scalable telomere-to-telomere assembly for diploid and polyploid genomes with double graph

1 code implementation6 Jun 2023 Haoyu Cheng, Mobin Asri, Julian Lucas, Sergey Koren, Heng Li

Despite recent advances in the length and the accuracy of long-read data, building haplotype-resolved genome assemblies from telomere to telomere still requires considerable computational resources.

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