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Detailed Balance for Particle Models of Reversible Reactions in Bounded Domains
In bounded domains with no-flux boundary conditions, when choosing unbinding kernels consistent with several commonly used binding kernels, we show that preserving detailed balance of spatial reaction-fluxes at all points requires spatially varying unbinding rate functions near the domain boundary.
How Retroactivity Affects the Behavior of Incoherent Feed-Forward Loops
We compare the behaviors of IFFLs to negative autoregulatory loops, another sign-sensitive response-accelerating network motif, and find that increasing retroactivity in a negative autoregulated circuit can only slow the response.
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