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Found 4 papers, 1 papers with code
A picture guide to cancer progression and monotonic accumulation models: evolutionary assumptions, plausible interpretations, and alternative uses
They have been used in computational oncology and virology to understand dependencies in the accumulation of mutations but also in widely different problems such as malaria progression.
Global epistasis on fitness landscapes
Yet, patterns of global epistasis, in which the fitness effect of a mutation is well-predicted by the fitness of its genetic background, may actually be of help in our efforts to reconstruct fitness landscapes and infer adaptive trajectories.
From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution.
Molecular Signatures from Gene Expression Data
However, available methods to search for signatures fail to address key requirements of signatures, especially the discovery of sets of tightly coexpressed genes.
Quantitative Methods Genomics
