Search Results for author: Philip Payne

Found 6 papers, 0 papers with code

HiMAL: A Multimodal Hierarchical Multi-task Auxiliary Learning framework for predicting and explaining Alzheimer disease progression

no code implementations4 Apr 2024 Sayantan Kumar, Sean Yu, Andrew Michelson, Thomas Kannampallil, Philip Payne

Discussion: Clinically informative model explanations anticipate cognitive decline 6 months in advance, aiding clinicians in future disease progression assessment.

Multi-Task Learning

Analysing heterogeneity in Alzheimer Disease using multimodal normative modelling on ATN biomarkers

no code implementations4 Apr 2024 Sayantan Kumara, Thomas Earnest, Braden Yang, Deydeep Kothapalli, Tammie L. S. Benzinger, Brian A. Gordon, Philip Payne, Aristeidis Sotiras

ADS individuals with moderate or severe dementia showed higher proportion of regional outliers for each modality as well as more dissimilarity in modality-specific regional outlier patterns compared to ADS individuals with early or mild dementia.

Improving Normative Modeling for Multi-modal Neuroimaging Data using mixture-of-product-of-experts variational autoencoders

no code implementations2 Dec 2023 Sayantan Kumar, Philip Payne, Aristeidis Sotiras

Normative models in neuroimaging learn the brain patterns of healthy population distribution and estimate how disease subjects like Alzheimer's Disease (AD) deviate from the norm.

Assisting Clinical Decisions for Scarcely Available Treatment via Disentangled Latent Representation

no code implementations6 Jul 2023 Bing Xue, Ahmed Sameh Said, Ziqi Xu, Hanyang Liu, Neel Shah, Hanqing Yang, Philip Payne, Chenyang Lu

TVAE is specifically designed to address the modeling challenges like ECMO with strong treatment selection bias and scarce treatment cases.

counterfactual Selection bias

Identifying Dementia Subtypes with Electronic Health Records

no code implementations31 Jan 2022 Sayantan Kumar, Zachary Abrams, Suzanne Schindler, Nupur Ghoshal, Philip Payne

Our results indicate both inter-subtype variability, which indicates the variability amongst dementia subtypes for a particular component score even with the same CDR and (ii) intra-subtype variability, which indicates the variation in the 6 component scores within a particular dementia subtype.

Normative Modeling using Multimodal Variational Autoencoders to Identify Abnormal Brain Structural Patterns in Alzheimer Disease

no code implementations10 Oct 2021 Sayantan Kumar, Philip Payne, Aristeidis Sotiras

However, existing deep learning based normative models on multimodal MRI data use unimodal autoencoders with a single encoder and decoder that may fail to capture the relationship between brain measurements extracted from different MRI modalities.

GPR

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