Search Results for author: Pan Tan

Found 8 papers, 2 papers with code

Simple, Efficient and Scalable Structure-aware Adapter Boosts Protein Language Models

1 code implementation23 Apr 2024 Yang Tan, Mingchen Li, Bingxin Zhou, Bozitao Zhong, Lirong Zheng, Pan Tan, Ziyi Zhou, Huiqun Yu, Guisheng Fan, Liang Hong

Fine-tuning Pre-trained protein language models (PLMs) has emerged as a prominent strategy for enhancing downstream prediction tasks, often outperforming traditional supervised learning approaches.

Representation Learning

PETA: Evaluating the Impact of Protein Transfer Learning with Sub-word Tokenization on Downstream Applications

1 code implementation26 Oct 2023 Yang Tan, Mingchen Li, Pan Tan, Ziyi Zhou, Huiqun Yu, Guisheng Fan, Liang Hong

Moreover, despite the wealth of benchmarks and studies in the natural language community, there remains a lack of a comprehensive benchmark for systematically evaluating protein language model quality.

Protein Language Model Transfer Learning

Accurate and Definite Mutational Effect Prediction with Lightweight Equivariant Graph Neural Networks

no code implementations13 Apr 2023 Bingxin Zhou, Outongyi Lv, Kai Yi, Xinye Xiong, Pan Tan, Liang Hong, Yu Guang Wang

Directed evolution as a widely-used engineering strategy faces obstacles in finding desired mutants from the massive size of candidate modifications.

Graph Representation Learning

TemPL: A Novel Deep Learning Model for Zero-Shot Prediction of Protein Stability and Activity Based on Temperature-Guided Language Modeling

no code implementations7 Apr 2023 Pan Tan, Mingchen Li, Liang Zhang, Zhiqiang Hu, Liang Hong

We introduce TemPL, a novel deep learning approach for zero-shot prediction of protein stability and activity, harnessing temperature-guided language modeling.

Language Modelling

SESNet: sequence-structure feature-integrated deep learning method for data-efficient protein engineering

no code implementations29 Dec 2022 Mingchen Li, Liqi Kang, Yi Xiong, Yu Guang Wang, Guisheng Fan, Pan Tan, Liang Hong

Here, we develop SESNet, a supervised deep-learning model to predict the fitness for protein mutants by leveraging both sequence and structure information, and exploiting attention mechanism.

Data Augmentation

InterFace:Adjustable Angular Margin Inter-class Loss for Deep Face Recognition

no code implementations5 Oct 2022 Meng Sang, Jiaxuan Chen, Mengzhen Li, Pan Tan, Anning Pan, Shan Zhao, Yang Yang

In the field of face recognition, it is always a hot research topic to improve the loss solution to make the face features extracted by the network have greater discriminative power.

Face Model Face Recognition

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