Search Results for author: Ngoc Hieu Tran

Found 7 papers, 6 papers with code

PointIso: Point Cloud Based Deep Learning Model for Detecting Arbitrary-Precision Peptide Features in LC-MS Map through Attention Based Segmentation

1 code implementation15 Sep 2020 Fatema Tuz Zohora, M Ziaur Rahman, Ngoc Hieu Tran, Lei Xin, Baozhen Shan, Ming Li

A promising technique of discovering disease biomarkers is to measure the relative protein abundance in multiple biofluid samples through liquid chromatography with tandem mass spectrometry (LC-MS/MS) based quantitative proteomics.

DeepNovoV2: Better de novo peptide sequencing with deep learning

1 code implementation17 Apr 2019 Rui Qiao, Ngoc Hieu Tran, Lei Xin, Baozhen Shan, Ming Li, Ali Ghodsi

Personalized cancer vaccines are envisioned as the next generation rational cancer immunotherapy.

de novo peptide sequencing

DeepIso: A Deep Learning Model for Peptide Feature Detection

no code implementations9 Dec 2017 Fatema Tuz Zohora, Ngoc Hieu Tran, Xianglilan Zhang, Lei Xin, Baozhen Shan, Ming Li

In this paper we propose a novel deep learning based model, DeepIso, that uses Convolutional Neural Networks (CNNs) to scan an LC-MS map to detect peptide features and estimate their abundance.

Drug Discovery Specificity

Protein identification with deep learning: from abc to xyz

1 code implementation8 Oct 2017 Ngoc Hieu Tran, Zachariah Levine, Lei Xin, Baozhen Shan, Ming Li

We combine two modules de novo sequencing and database search into a single deep learning framework for peptide identification, and integrate de Bruijn graph assembly technique to offer a complete solution to reconstruct protein sequences from tandem mass spectrometry data.

de novo peptide sequencing

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