Search Results for author: Mary Lesperance

Found 4 papers, 0 papers with code

Handling highly correlated genes in prediction analysis of genomic studies

no code implementations5 Jul 2020 Li Xing, Songwan Joun, Kurt Mackay, Mary Lesperance, Xuekui Zhang

Method: We propose a grouping algorithm, which treats highly correlated genes as a group and uses their common pattern to represent the group's biological signal in feature selection.

feature selection

Simultaneous prediction of multiple outcomes using revised stacking algorithms

no code implementations29 Jan 2019 Li Xing, Mary Lesperance, Xuekui Zhang

Our goal is to build a model using data in this database, which simultaneously predicts the resistance of multiple drugs using mutation information from sequences of viruses for any new patient.

A Bayesian Group Sparse Multi-Task Regression Model for Imaging Genetics

no code implementations7 May 2016 Keelin Greenlaw, Elena Szefer, Jinko Graham, Mary Lesperance, Farouk S. Nathoo

Results: We develop a Bayesian hierarchical modeling formulation where the posterior mode corresponds to the estimator proposed by Wang et al. (Bioinformatics, 2012), and an approach that allows for full posterior inference including the construction of interval estimates for the regression parameters.

regression

Regularization Parameter Selection for a Bayesian Multi-Level Group Lasso Regression Model with Application to Imaging Genomics

no code implementations27 Mar 2016 Farouk S. Nathoo, Keelin Greenlaw, Mary Lesperance

We demonstrate these problems through simulation examples and study an approximation to the marginal likelihood which sheds light on the cause of this problem.

regression

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