Eliciting judgements about dependent quantities of interest: The SHELF extension and copula methods illustrated using an asthma case study

no code implementations • 4 Feb 2021 • Björn Holzhauer, Lisa V. Hampson, John Paul Gosling, Björn Bornkamp, Joseph Kahn, Markus R. Lange, Wen-Lin Luo, Caterina Brindicci, David Lawrence, Steffen Ballerstedt, Anthony O'Hagan

The first approach elicits experts' judgements about a quantity of interest conditional on knowledge about another one.

A Bayesian hierarchical model for bridging across patient subgroups in phase I clinical trials with animal data

no code implementations • 13 Nov 2019 • Haiyan Zheng, Lisa V. Hampson, Thomas Jaki

This leads to feasible exchangeability assumptions that the parameter vectors, which underpin the dose-toxicity relationship per study, are assumed to be drawn from a common distribution.

Methodology Applications