Search Results for author: Linwei Wang

Found 30 papers, 11 papers with code

HyPer-EP: Meta-Learning Hybrid Personalized Models for Cardiac Electrophysiology

no code implementations15 Mar 2024 Xiajun Jiang, Sumeet Vadhavkar, Yubo Ye, Maryam Toloubidokhti, Ryan Missel, Linwei Wang

Personalized virtual heart models have demonstrated increasing potential for clinical use, although the estimation of their parameters given patient-specific data remain a challenge.

Meta-Learning

Unsupervised Learning of Hybrid Latent Dynamics: A Learn-to-Identify Framework

no code implementations13 Mar 2024 Yubo Ye, Sumeet Vadhavkar, Xiajun Jiang, Ryan Missel, Huafeng Liu, Linwei Wang

Modern applications increasingly require unsupervised learning of latent dynamics from high-dimensional time-series.

Inductive Bias Meta-Learning +1

Hybrid Kinetics Embedding Framework for Dynamic PET Reconstruction

no code implementations12 Mar 2024 Yubo Ye, Huafeng Liu, Linwei Wang

We then embed this hybrid model at the latent space of an encoding-decoding framework to enable both supervised and unsupervised identification of the hybrid kinetics and thereby dynamic PET reconstruction.

LIBR+: Improving Intraoperative Liver Registration by Learning the Residual of Biomechanics-Based Deformable Registration

no code implementations11 Mar 2024 Dingrong Wang, Soheil Azadvar, Jon Heiselman, Xiajun Jiang, Michael Miga, Linwei Wang

The surgical environment imposes unique challenges to the intraoperative registration of organ shapes to their preoperatively-imaged geometry.

Distributionally Robust Optimization and Invariant Representation Learning for Addressing Subgroup Underrepresentation: Mechanisms and Limitations

no code implementations12 Aug 2023 Nilesh Kumar, Ruby Shrestha, Zhiyuan Li, Linwei Wang

Spurious correlation caused by subgroup underrepresentation has received increasing attention as a source of bias that can be perpetuated by deep neural networks (DNNs).

Image Classification Medical Image Classification +1

Learning Transferable Object-Centric Diffeomorphic Transformations for Data Augmentation in Medical Image Segmentation

no code implementations25 Jul 2023 Nilesh Kumar, Prashnna K. Gyawali, Sandesh Ghimire, Linwei Wang

To this end, we propose a novel object-centric data augmentation model that is able to learn the shape variations for the objects of interest and augment the object in place without modifying the rest of the image.

Data Augmentation Image Segmentation +4

Sequential Latent Variable Models for Few-Shot High-Dimensional Time-Series Forecasting

1 code implementation ICLR 2023 Xiajun Jiang, Ryan Missel, Zhiyuan Li, Linwei Wang

We compared the presented framework with a comprehensive set of baseline models trained 1) globally on the large meta-training set with diverse dynamics, and 2) individually on single dynamics, both with and without fine-tuning to k-shot support series used by the meta-models.

Meta-Learning Time Series +1

Interpretable Modeling and Reduction of Unknown Errors in Mechanistic Operators

no code implementations2 Nov 2022 Maryam Toloubidokhti, Nilesh Kumar, Zhiyuan Li, Prashnna K. Gyawali, Brian Zenger, Wilson W. Good, Rob S. MacLeod, Linwei Wang

Prior knowledge about the imaging physics provides a mechanistic forward operator that plays an important role in image reconstruction, although myriad sources of possible errors in the operator could negatively impact the reconstruction solutions.

Image Reconstruction

Few-shot Generation of Personalized Neural Surrogates for Cardiac Simulation via Bayesian Meta-Learning

1 code implementation6 Oct 2022 Xiajun Jiang, Zhiyuan Li, Ryan Missel, Md Shakil Zaman, Brian Zenger, Wilson W. Good, Rob S. MacLeod, John L. Sapp, Linwei Wang

As test time, metaPNS delivers a personalized neural surrogate by fast feed-forward embedding of a small and flexible number of data available from an individual, achieving -- for the first time -- personalization and surrogate construction for expensive simulations in one end-to-end learning framework.

Meta-Learning Variational Inference

Neural State-Space Modeling with Latent Causal-Effect Disentanglement

1 code implementation26 Sep 2022 Maryam Toloubidokhti, Ryan Missel, Xiajun Jiang, Niels Otani, Linwei Wang

In a novel neural formulation of state-space models (SSMs), we first introduce causal-effect modeling of the latent dynamics via a system of interacting neural ODEs that separately describes 1) the continuous-time dynamics of the internal intervention, and 2) its effect on the trajectory of the system's native state.

Disentanglement Time Series Analysis

Fast Posterior Estimation of Cardiac Electrophysiological Model Parameters via Bayesian Active Learning

no code implementations13 Oct 2021 Md Shakil Zaman, Jwala Dhamala, Pradeep Bajracharya, John L. Sapp, B. Milan Horacek, Katherine C. Wu, Natalia A. Trayanova, Linwei Wang

In this paper, we present a Bayesian active learning method to directly approximate the posterior pdf function of cardiac model parameters, in which we intelligently select training points to query the simulation model in order to learn the posterior pdf using a small number of samples.

Active Learning

Semi-Supervised Learning for Eye Image Segmentation

no code implementations17 Mar 2021 Aayush K. Chaudhary, Prashnna K. Gyawali, Linwei Wang, Jeff B. Pelz

Recent advances in appearance-based models have shown improved eye tracking performance in difficult scenarios like occlusion due to eyelashes, eyelids or camera placement, and environmental reflections on the cornea and glasses.

Image Segmentation Segmentation +1

Enhancing Mixup-based Semi-Supervised Learning with Explicit Lipschitz Regularization

1 code implementation23 Sep 2020 Prashnna Kumar Gyawali, Sandesh Ghimire, Linwei Wang

On three benchmark data sets and one real-world biomedical data set, we demonstrate that this combined regularization results in improved generalization performance of SSL when learning from a small amount of labeled data.

Learning Geometry-Dependent and Physics-Based Inverse Image Reconstruction

no code implementations18 Jul 2020 Xiajun Jiang, Sandesh Ghimire, Jwala Dhamala, Zhiyuan Li, Prashnna Kumar Gyawali, Linwei Wang

However, many reconstruction problems involve imaging physics that are dependent on the underlying non-Euclidean geometry.

Image Reconstruction

Quantifying the Uncertainty in Model Parameters Using Gaussian Process-Based Markov Chain Monte Carlo: An Application to Cardiac Electrophysiological Models

no code implementations2 Jun 2020 Jwala Dhamala, John L. Sapp, B. Milan Horácek, Linwei Wang

However, by sampling from an approximation of the exact posterior probability density function (pdf) of the parameters, the efficiency is gained at the expense of sampling accuracy.

Computational Efficiency

Semi-supervised Medical Image Classification with Global Latent Mixing

1 code implementation22 May 2020 Prashnna Kumar Gyawali, Sandesh Ghimire, Pradeep Bajracharya, Zhiyuan Li, Linwei Wang

In this work, we argue that regularizing the global smoothness of neural functions by filling the void in between data points can further improve SSL.

General Classification Image Classification +1

Analysis of Discriminator in RKHS Function Space for Kullback-Leibler Divergence Estimation

no code implementations25 Feb 2020 Sandesh Ghimire, Prashnna K Gyawali, Linwei Wang

Based on this theory, we then present a scalable way to control the complexity of the discriminator for a reliable estimation of KL divergence.

Generative Adversarial Network

Progressive Learning and Disentanglement of Hierarchical Representations

1 code implementation ICLR 2020 Zhiyuan Li, Jaideep Vitthal Murkute, Prashnna Kumar Gyawali, Linwei Wang

By drawing on the respective advantage of hierarchical representation learning and progressive learning, this is to our knowledge the first attempt to improve disentanglement by progressively growing the capacity of VAE to learn hierarchical representations.

Disentanglement

Venue-based HIV testing at sex work hotspots to reach adolescent girls and young women living with HIV: a cross-sectional study in Mombasa, Kenya

no code implementations10 Dec 2019 Huiting Ma, Linwei Wang, Peter Gichangi, Vernon Mochache, Griffins Manguro, Helgar K Musyoki, Parinita Bhattacharjee, François Cholette, Paul Sandstrom, Marissa L Becker, Sharmistha Mishra

We compared the HIV cascade among AGYW who sell sex (YSW, N=408) versus those who do not (NSW, N=891); and triangulated the potential (100% test acceptance and accuracy) and feasible (accounting for test acceptance and sensitivity) number of AGYW that could be newly diagnosed via hotspot-based HIV rapid testing in Mombasa.

Wavelets to the Rescue: Improving Sample Quality of Latent Variable Deep Generative Models

no code implementations26 Oct 2019 Prashnna K Gyawali, Rudra Shah, Linwei Wang, VSR Veeravasarapu, Maneesh Singh

Variational Autoencoders (VAE) are probabilistic deep generative models underpinned by elegant theory, stable training processes, and meaningful manifold representations.

Improving Disentangled Representation Learning with the Beta Bernoulli Process

1 code implementation3 Sep 2019 Prashnna Kumar Gyawali, Zhiyuan Li, Cameron Knight, Sandesh Ghimire, B. Milan Horacek, John Sapp, Linwei Wang

We note that the independence within and the complexity of the latent density are two different properties we constrain when regularizing the posterior density: while the former promotes the disentangling ability of VAE, the latter -- if overly limited -- creates an unnecessary competition with the data reconstruction objective in VAE.

Decision Making Representation Learning

Semi-Supervised Learning by Disentangling and Self-Ensembling Over Stochastic Latent Space

1 code implementation22 Jul 2019 Prashnna Kumar Gyawali, Zhiyuan Li, Sandesh Ghimire, Linwei Wang

In this work, we hypothesize -- from the generalization perspective -- that self-ensembling can be improved by exploiting the stochasticity of a disentangled latent space.

Data Augmentation Multi-Label Classification +1

Bayesian Optimization on Large Graphs via a Graph Convolutional Generative Model: Application in Cardiac Model Personalization

1 code implementation1 Jul 2019 Jwala Dhamala, Sandesh Ghimire, John L. Sapp, B. Milan Horacek, Linwei Wang

In this paper, we present a novel graph convolutional VAE to allow generative modeling of non-Euclidean data, and utilize it to embed Bayesian optimization of large graphs into a small latent space.

Bayesian Optimization

Generative Modeling and Inverse Imaging of Cardiac Transmembrane Potential

no code implementations12 May 2019 Sandesh Ghimire, Jwala Dhamala, Prashnna Kumar Gyawali, John L. Sapp, B. Milan Horacek, Linwei Wang

We introduce a novel model-constrained inference framework that replaces conventional physiological models with a deep generative model trained to generate TMP sequences from low-dimensional generative factors.

Deep Generative Model with Beta Bernoulli Process for Modeling and Learning Confounding Factors

no code implementations31 Oct 2018 Prashnna K Gyawali, Cameron Knight, Sandesh Ghimire, B. Milan Horacek, John L. Sapp, Linwei Wang

While deep representation learning has become increasingly capable of separating task-relevant representations from other confounding factors in the data, two significant challenges remain.

Representation Learning

Improving Generalization of Sequence Encoder-Decoder Networks for Inverse Imaging of Cardiac Transmembrane Potential

no code implementations12 Oct 2018 Sandesh Ghimire, Prashnna Kumar Gyawali, John L. Sapp, Milan Horacek, Linwei Wang

The results demonstrate that the generalization ability of an inverse reconstruction network can be improved by constrained stochasticity combined with global aggregation of temporal information in the latent space.

Learning Theory

Learning disentangled representation from 12-lead electrograms: application in localizing the origin of Ventricular Tachycardia

1 code implementation4 Aug 2018 Prashnna K Gyawali, B. Milan Horacek, John L. Sapp, Linwei Wang

In this work, we present a conditional variational autoencoder (VAE) to extract the subject-specific adjustment to the ECG data, conditioned on task-specific representations learned from a deterministic encoder.

Total-Variation Minimization on Unstructured Volumetric Mesh: Biophysical Applications on Reconstruction of 3D Ischemic Myocardium

no code implementations CVPR 2014 Jingjia Xu, Azar Rahimi Dehaghani, Fei Gao, Linwei Wang

This paper describes the development and application of a new approach to total-variation (TV) minimization for reconstruction problems on geometrically-complex and unstructured volumetric mesh.

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