Search Results for author: Lida Zhu

Found 2 papers, 0 papers with code

Improving PTM Site Prediction by Coupling of Multi-Granularity Structure and Multi-Scale Sequence Representation

no code implementations4 Jan 2024 Zhengyi Li, Menglu Li, Lida Zhu, Wen Zhang

Specifically, multigranularity structure-aware representation learning is designed to learn neighborhood structure representations at the amino acid, atom, and whole protein granularity from AlphaFold predicted structures, followed by utilizing contrastive learning to optimize the structure representations. Additionally, multi-scale sequence representation learning is used to extract context sequence information, and motif generated by aligning all context sequences of PTM sites assists the prediction.

Contrastive Learning Representation Learning

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