no code implementations • 4 Jan 2024 • Zhengyi Li, Menglu Li, Lida Zhu, Wen Zhang
Specifically, multigranularity structure-aware representation learning is designed to learn neighborhood structure representations at the amino acid, atom, and whole protein granularity from AlphaFold predicted structures, followed by utilizing contrastive learning to optimize the structure representations. Additionally, multi-scale sequence representation learning is used to extract context sequence information, and motif generated by aligning all context sequences of PTM sites assists the prediction.
no code implementations • 11 Oct 2023 • Shuoying Wei, Xinlong Wen, Lida Zhu, Songquan Li, Rongbo Zhu
On the other hand, CCD describes the data which has inconsistent label among the original data.