1 code implementation • 6 Sep 2018 • Juvid Aryaman, Charlotte Bowles, Nick S. Jones, Iain G. Johnston
The role of the resulting mitochondrial networks in the time evolution of the cellular proportion of mutated mtDNA molecules (heteroplasmy), and cell-to-cell variability in heteroplasmy (heteroplasmy variance), remains incompletely understood.
no code implementations • 6 Sep 2018 • Juvid Aryaman, Iain G. Johnston, Nick S. Jones
The diverse sources of mitochondrial heterogeneity, as well as their increasingly recognised role in contributing to cellular heterogeneity, highlights the need for future single-cell mitochondrial measurements in the context of cellular noise studies.