no code implementations • 26 Mar 2022 • Jianhua Xing
Cells with the same genome can exist in different phenotypes.
no code implementations • 8 Jul 2021 • Weikang Wang, Dante Poe, Ke Ni, Jianhua Xing
Phenotype transition takes place in many biological processes such as differentiation, and understanding how a cell reprograms its global gene expression profile is a problem of rate theories.
no code implementations • 25 Jul 2019 • Shubham Tripathi, Jianhua Xing, Herbert Levine, Mohit Kumar Jolly
Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels.
no code implementations • 20 Feb 2019 • Oleg Igoshin, Jing Chen, Jianhua Xing, Jian Liu, Timothy C. Elston, Michael Grabe, Kenneth S. Kim, Jasmine Nirody, Padmini Rangamani, Sean Sun, Hongyun Wang, Charles Wolgemuth
Over the past 50 years, the use of mathematical models, derived from physical reasoning, to describe molecular and cellular systems has evolved from an art of the few to a cornerstone of biological inquiry.
no code implementations • 18 Jan 2019 • Jingyu Zhang, HengYu Chen, Ruoyan Li, David A. Taft, Guang Yao, Fan Bai, Jianhua Xing
Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes.