1 code implementation • 21 Dec 2023 • Alex Morehead, Jeffrey Ruffolo, Aadyot Bhatnagar, Ali Madani
In this work, we introduce MMDiff, a generative model that jointly designs sequences and structures of nucleic acid and protein complexes, independently or in complex, using joint SE(3)-discrete diffusion noise.
4 code implementations • 27 Jun 2022 • Erik Nijkamp, Jeffrey Ruffolo, Eli N. Weinstein, Nikhil Naik, Ali Madani
Attention-based models trained on protein sequences have demonstrated incredible success at classification and generation tasks relevant for artificial intelligence-driven protein design.