Search Results for author: Jacob M. Luber

Found 7 papers, 3 papers with code

Vulnerabilities Unveiled: Adversarially Attacking a Multimodal Vision Language Model for Pathology Imaging

no code implementations4 Jan 2024 Jai Prakash Veerla, Poojitha Thota, Partha Sai Guttikonda, Shirin Nilizadeh, Jacob M. Luber

In the dynamic landscape of medical artificial intelligence, this study explores the vulnerabilities of the Pathology Language-Image Pretraining (PLIP) model, a Vision Language Foundation model, under targeted adversarial conditions.

Domain Adaptation Language Modelling

Predicting Future States with Spatial Point Processes in Single Molecule Resolution Spatial Transcriptomics

no code implementations4 Jan 2024 Parisa Boodaghi Malidarreh, Biraaj Rout, Mohammad Sadegh Nasr, Priyanshi Borad, Jillur Rahman Saurav, Jai Prakash Veerla, Kelli Fenelon, Theodora Koromila, Jacob M. Luber

In this paper, we introduce a pipeline based on Random Forest Regression to predict the future distribution of cells that are expressed by the Sog-D gene (active cells) in both the Anterior to posterior (AP) and the Dorsal to Ventral (DV) axis of the Drosophila in embryogenesis process.

Point Processes regression +1

Generalizability of PRS313 for breast cancer risk amongst non-Europeans in a Los Angeles biobank

no code implementations6 May 2023 Helen Shang, Yi Ding, Vidhya Venkateswaran, Kristin Boulier, Nikhita Kathuria-Prakash, Parisa Boodaghi Malidarreh, Jacob M. Luber, Bogdan Pasaniuc

We found that the PRS313 achieved overlapping Areas under the ROC Curve (AUCs) in females of Lantix (AUC, 0. 68; 95 CI, 0. 65-0. 71) and European ancestry (AUC, 0. 70; 95 CI, 0. 69-0. 71) but lower AUCs for the AFR and EAA populations (AFR: AUC, 0. 61; 95 CI, 0. 56-0. 65; EAA: AUC, 0. 64; 95 CI, 0. 60-0. 680).

Clinically Relevant Latent Space Embedding of Cancer Histopathology Slides through Variational Autoencoder Based Image Compression

1 code implementation23 Mar 2023 Mohammad Sadegh Nasr, Amir Hajighasemi, Paul Koomey, Parisa Boodaghi Malidarreh, Michael Robben, Jillur Rahman Saurav, Helen H. Shang, Manfred Huber, Jacob M. Luber

We generate and visualize embeddings from the compressed latent space and demonstrate how they are useful for clinical interpretation of data, and how in the future such latent embeddings can be used to accelerate search of clinical imaging data.

Image Compression

A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels

2 code implementations20 May 2022 Jillur Rahman Saurav, Mohammad Sadegh Nasr, Paul Koomey, Michael Robben, Manfred Huber, Jon Weidanz, Bríd Ryan, Eytan Ruppin, Peng Jiang, Jacob M. Luber

We validate these claims by generating a new experimental spatial proteomics data set from human lung adenocarcinoma tissue sections and show that a model trained on HuBMAP can accurately synthesize channels from our new data set.

Ethics Generative Adversarial Network +2

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