no code implementations • 4 Dec 2023 • Sophia Krix, Ella Wilczynski, Neus Falgàs, Raquel Sánchez-Valle, Eti Yoles, Uri Nevo, Kuti Baruch, Holger Fröhlich
Here, we give a background on advances in research on brain-immune system cross-talk in Alzheimer's disease and review recent machine learning and mechanistic modeling approaches which leverage modern omics technologies for blood-based immune system-related biomarker discovery.
1 code implementation • 12 May 2023 • Lisa Kühnel, Julian Schneider, Ines Perrar, Tim Adams, Fabian Prasser, Ute Nöthlings, Holger Fröhlich, Juliane Fluck
In this study, we use a state-of-the-art synthetic data generation method and perform in-depth quality analyses of the generated data for a specific use case in the field of nutrition.
2 code implementations • GigaScience 2019 • Johann de Jong, Mohammad Asif Emon, Ping Wu, Reagon Karki, Meemansa Sood, Patrice Godard, Ashar Ahmad, Henri Vrooman, Martin Hofmann-Apitius, Holger Fröhlich
Findings The problem of clustering multivariate short time series with many missing values is generally not well addressed in the literature.
no code implementations • 13 Dec 2012 • Yupeng Cun, Holger Fröhlich
We extendd our approach further by integrating information on candidate disease genes and targets of disease associated Transcript Factors (TFs).