Search Results for author: Henry Brodaty

Found 5 papers, 0 papers with code

Sex Differences in 6-Year Progression of White Matter Hyperintensities in Non-Demented Older Adults: Sydney Memory and Ageing Study

no code implementations17 Jul 2023 Abdullah Alqarni, Wei Wen, Ben C. P. Lam, Nicole Kochan, Henry Brodaty, Perminder S. Sachdev, Jiyang Jiang

Conclusion: The findings highlighted sex differences in the associations between WMH progression and cognition decline over time, suggesting sex-specific strategies in managing WMH accumulations in ageing.

Temporal Pattern Mining for Analysis of Longitudinal Clinical Data: Identifying Risk Factors for Alzheimer's Disease

no code implementations11 Sep 2022 Annette Spooner, Gelareh Mohammadi, Perminder S. Sachdev, Henry Brodaty, Arcot Sowmya

This method uses temporal abstraction to convert the data into a more appropriate form for modelling, temporal pattern mining, to discover patterns in the complex, longitudinal data and machine learning models of survival analysis to select the discovered patterns.

Survival Analysis

Ensemble feature selection with clustering for analysis of high-dimensional, correlated clinical data in the search for Alzheimer's disease biomarkers

no code implementations6 Jul 2022 Annette Spooner, Gelareh Mohammadi, Perminder S. Sachdev, Henry Brodaty, Arcot Sowmya

When feature selection is applied to these datasets to identify the most important features, the biases inherent in some multivariate feature selectors due to correlated features make it difficult for these methods to distinguish between the important and irrelevant features and the results of the feature selection process can be unstable.

Clustering feature selection

Ensemble feature selection with data-driven thresholding for Alzheimer's disease biomarker discovery

no code implementations5 Jul 2022 Annette Spooner, Gelareh Mohammadi, Perminder S. Sachdev, Henry Brodaty, Arcot Sowmya

A fixed threshold, which is typically applied, offers no guarantee that the final set of selected features contains only relevant features.

feature selection

Network resilience in the aging brain

no code implementations3 Feb 2022 Tao Liu, Shu Guo, Hao liu, Rui Kang, Mingyang Bai, Jiyang Jiang, Wei Wen, Xing Pan, Jun Tai, JianXin Li, Jian Cheng, Jing Jing, Zhenzhou Wu, Haijun Niu, Haogang Zhu, Zixiao Li, Yongjun Wang, Henry Brodaty, Perminder Sachdev, Daqing Li

Degeneration and adaptation are two competing sides of the same coin called resilience in the progressive processes of brain aging or diseases.

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