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Found 5 papers, 1 papers with code
Evaluating the roughness of structure-property relationships using pretrained molecular representations
When the correlation between structure and property weakens, a dataset is described as "rough," but this characteristic is partly a function of the chosen representation.
Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype
We show that a highly cooperative (Hill coefficient 2. 5) in vivo activity of Thymidylate Kinase (Tmk), a downstream enzyme that phosphorylates dTMP to dTDP, is the cause of suboptimal dTTP levels.
A native chemical chaperone in the human eye lens
Cataract is one of the most prevalent protein aggregation disorders and still the biggest cause of vision loss worldwide.
Accelerating high-throughput virtual screening through molecular pool-based active learning
Structure-based virtual screening is an important tool in early stage drug discovery that scores the interactions between a target protein and candidate ligands.
Effect of protein structure on evolution of cotranslational folding
Low contact order proteins evolve to fold cotranslationally.
