Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects

no code implementations • 10 Jul 2023 • Erdi Kara, T. L. Jackson, Chartese Jones, Reginald L. McGee II, Rockford Sison

A critical question for solving the heterogeneity problem is whether CAR T therapy induces bystander effects, such as antigen spreading.

Deep Learning Based Object Tracking in Walking Droplet and Granular Intruder Experiments

1 code implementation • 27 Jan 2023 • Erdi Kara, George Zhang, Joseph J. Williams, Gonzalo Ferrandez-Quinto, Leviticus J. Rhoden, Maximilian Kim, J. Nathan Kutz, Aminur Rahman

We present a deep-learning based tracking objects of interest in walking droplet and granular intruder experiments.

object-detection Object Detection +1

Tumor ablation due to inhomogeneous -- anisotropic diffusion in generic 3-dimensional topologies

no code implementations • 10 Dec 2019 • Erdi Kara, Aminur Rahman, Eugenio Aulisa, Souparno Ghosh

We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model.

Medical Physics Tissues and Organs