Search Results for author: Ellen D. Zhong

Found 5 papers, 2 papers with code

Amortized Inference for Heterogeneous Reconstruction in Cryo-EM

no code implementations13 Oct 2022 Axel Levy, Gordon Wetzstein, Julien Martel, Frederic Poitevin, Ellen D. Zhong

Cryo-electron microscopy (cryo-EM) is an imaging modality that provides unique insights into the dynamics of proteins and other building blocks of life.

Exploring generative atomic models in cryo-EM reconstruction

no code implementations3 Jul 2021 Ellen D. Zhong, Adam Lerer, Joseph H. Davis, Bonnie Berger

Although reconstruction algorithms typically model the 3D volume as a generic function parameterized as a voxel array or neural network, the underlying atomic structure of the protein of interest places well-defined physical constraints on the reconstructed structure.

Protein Folding

CryoDRGN2: Ab Initio Neural Reconstruction of 3D Protein Structures From Real Cryo-EM Images

no code implementations ICCV 2021 Ellen D. Zhong, Adam Lerer, Joseph H. Davis, Bonnie Berger

In this work we describe cryoDRGN2, an ab initio reconstruction algorithm, which can jointly estimate image poses and learn a neural model of a distribution of 3D structures on real heterogeneous cryo-EM data.

Explicitly disentangling image content from translation and rotation with spatial-VAE

1 code implementation NeurIPS 2019 Tristan Bepler, Ellen D. Zhong, Kotaro Kelley, Edward Brignole, Bonnie Berger

Given an image dataset, we are often interested in finding data generative factors that encode semantic content independently from pose variables such as rotation and translation.

Disentanglement Translation

Reconstructing continuous distributions of 3D protein structure from cryo-EM images

2 code implementations ICLR 2020 Ellen D. Zhong, Tristan Bepler, Joseph H. Davis, Bonnie Berger

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structure of proteins and other macromolecular complexes at near-atomic resolution.

3D Volumetric Reconstruction Clustering +2

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