1 code implementation • 25 Jun 2021 • Zoe Guan, Giovanni Parmigiani, Danielle Braun, Lorenzo Trippa
We validate the models using data from the Cancer Genetics Network.
1 code implementation • 13 May 2021 • Theodore Huang, Gregory Idos, Christine Hong, Stephen Gruber, Giovanni Parmigiani, Danielle Braun
Via simulations we show that integration of gradient boosting with an existing Mendelian model can produce an improved model that outperforms both that model and the model built using gradient boosting alone.
no code implementations • 24 Apr 2019 • Yujia Bao, Zhengyi Deng, Yan Wang, Heeyoon Kim, Victor Diego Armengol, Francisco Acevedo, Nofal Ouardaoui, Cathy Wang, Giovanni Parmigiani, Regina Barzilay, Danielle Braun, Kevin S. Hughes
We developed and evaluated two machine learning models to classify abstracts as relevant to the penetrance (risk of cancer for germline mutation carriers) or prevalence of germline genetic mutations.
1 code implementation • 17 Dec 2018 • Xiao Wu, Fabrizia Mealli, Marianthi-Anna Kioumourtzoglou, Francesca Dominici, Danielle Braun
We apply our proposed method to estimate the average causal exposure-response function between long-term PM$_{2. 5}$ exposure and all-cause mortality among 68. 5 million Medicare enrollees, 2000-2016.
Methodology Applications
no code implementations • 29 May 2018 • M. Benjamin Sabath, Qian Di, Danielle Braun, Joel Schwarz, Francesca Dominici, Christine Choirat
Fine particulate matter (PM$_{2. 5}$) is one of the criteria air pollutants regulated by the Environmental Protection Agency in the United States.
1 code implementation • 2 Dec 2017 • Xiao Wu, Danielle Braun, Marianthi-Anna Kioumourtzoglou, Christine Choirat, Qian Di, Francesca Dominici
We propose a new approach for estimating causal effects when the exposure is measured with error and confounding adjustment is performed via a generalized propensity score (GPS).
Methodology Applications