Search Results for author: Brian A. Camley

Found 7 papers, 0 papers with code

Nonlinear dynamics of confined cell migration -- modeling and inference

no code implementations10 Apr 2024 Pedrom Zadeh, Brian A. Camley

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates.

Does nematic order allow groups of elongated cells to sense electric fields better?

no code implementations6 Apr 2024 Kurmanbek Kaiyrbekov, Brian A. Camley

We model elongated cells that have a different accuracy sensing the field depending on their orientation with respect to the field.

Limits on the accuracy of contact inhibition of locomotion

no code implementations31 Oct 2023 Wei Wang, Brian A. Camley

However, in general, we find that cells have the ability to make reasonably reliable CIL decisions even for very narrow (micron-scale) contacts, even if the concentration of interfering ligands is ten times that of the correct ligands.

Tradeoffs in concentration sensing in dynamic environments

no code implementations29 Sep 2023 Aparajita Kashyap, Wei Wang, Brian A. Camley

However, when cells are in a environment that changes over time, past measurements may not reflect current conditions - creating a new source of error that trades off against noise in chemical sensing.

Collective gradient sensing with limited positional information

no code implementations19 Oct 2021 Emiliano Perez Ipiña, Brian A. Camley

As the cell positional uncertainty increases, there is a trade-off where the tug-of-war model responds more accurately to the chemical gradient.

Chemotaxis in uncertain environments: hedging bets with multiple receptor types

no code implementations24 Feb 2020 Austin Hopkins, Brian A. Camley

We show that, if a cell is exposed to a highly variable environment, it may gain chemotactic accuracy by expressing multiple receptor types with varying affinities for the same signal, as found commonly in chemotaxing cells like Dictyostelium.

Hydrodynamic Effects on the Motility of Crawling Eukaryotic Cells

no code implementations29 Aug 2019 Melissa H. Mai, Brian A. Camley

Our simple model of a cell, based on the three-sphere swimmer, is capable of both swimming and crawling.

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