Search Results for author: Bogdan Toader

Found 4 papers, 1 papers with code

On Manifold Learning in Plato's Cave: Remarks on Manifold Learning and Physical Phenomena

1 code implementation27 Apr 2023 Roy R. Lederman, Bogdan Toader

Many techniques in machine learning attempt explicitly or implicitly to infer a low-dimensional manifold structure of an underlying physical phenomenon from measurements without an explicit model of the phenomenon or the measurement apparatus.

Dimensionality Reduction

Methods for Cryo-EM Single Particle Reconstruction of Macromolecules having Continuous Heterogeneity

no code implementations19 Nov 2022 Bogdan Toader, Fred J. Sigworth, Roy R. Lederman

Macromolecules change their shape (conformation) in the process of carrying out their functions.

Integrating molecular models into CryoEM heterogeneity analysis using scalable high-resolution deep Gaussian mixture models

no code implementations18 Nov 2022 Muyuan Chen, Bogdan Toader, Roy Lederman

Resolving the structural variability of proteins is often key to understanding the structure-function relationship of those macromolecular machines.

Single Particle Analysis

Image reconstruction in light-sheet microscopy: spatially varying deconvolution and mixed noise

no code implementations8 Aug 2021 Bogdan Toader, Jerome Boulanger, Yury Korolev, Martin O. Lenz, James Manton, Carola-Bibiane Schonlieb, Leila Muresan

Then, we formulate a variational model that accounts for the combination of Poisson and Gaussian noise through a data fidelity term consisting of the infimal convolution of the single noise fidelities, first introduced in L. Calatroni et al. "Infimal convolution of data discrepancies for mixed noise removal", SIAM Journal on Imaging Sciences 10. 3 (2017), 1196-1233.

Image Reconstruction

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