no code implementations • 5 Jul 2020 • Sumanta Ray, Snehalika Lall, Anirban Mukhopadhyay, Sanghamitra Bandyopadhyay, Alexander Schönhuth
Here, we combine three networks, two of which are year-long curated, and one of which, on SARS-CoV-2-human host-virus protein interactions, was published only most recently (30th of April 2020), raising a novel network that puts drugs, human and virus proteins into mutual context.
no code implementations • 24 Dec 2019 • Marleen Balvert, Georgios Patoulidis, Andrew Patti, Timo M. Deist, Christine Eyler, Bas E. Dutilh, Alexander Schönhuth, David Craft
Our goal is to develop a method to identify the drug that is most promising based on a cell line's genomic information.
1 code implementation • ICLR 2018 • Bojian Yin, Marleen Balvert, Davide Zambrano, Alexander Schönhuth, Sander Bohte
The folding structure of the DNA molecule combined with helper molecules, also referred to as the chromatin, is highly relevant for the functional properties of DNA.
no code implementations • 19 Jan 2011 • Alexander Schönhuth
The generic identification problem is to decide whether a stochastic process $(X_t)$ is a hidden Markov process and if yes to infer its parameters for all but a subset of parametrizations that form a lower-dimensional subvariety in parameter space.