The evaluation of human epidermal growth factor receptor 2 (HER2) expression is essential to formulate a precise treatment for breast cancer. The routine evaluation of HER2 is conducted with immunohistochemical techniques (IHC), which is very expensive. Therefore, we propose a breast cancer immunohistochemical (BCI) benchmark attempting to synthesize IHC data directly with the paired hematoxylin and eosin (HE) stained images. The dataset contains 4870 registered image pairs, covering a variety of HER2 expression levels (0, 1+, 2+, 3+).
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This dataset includes sharp-blur pairs of Leishmania image, which is a protozoan parasite microscopy image dataset of Leishmania, obtained from the preserved slides stained with Giemsa. The paired blur-sharp images are acquired by employing a bright-field microscope (Olympus IX53) with 100× magnification oil immersion objectives.We first capture the sharp images as ground truth, then acquire its corresponding out-of-focus images. The extent and nature of defocusing are random along the optical axis, where the degree of out-of-focus is inconsistent from image-to-image. This dataset includes 764 in-focus and 764 corresponding out-of-focus images, where each image is composed of 2304 × 1728 pixels in 24-bit JPG format.
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