Three wild-type (C57BL/6J) male mice ran on a paper spool following odor trails (Mathis et al 2018). These experiments were carried out in the laboratory of Venkatesh N. Murthy at Harvard University. Data were recorded at 30 Hz with 640 x 480 pixels resolution acquired with a Point Grey Firefly FMVU-03MTM-CS. One human annotator was instructed to localize the 12 keypoints (snout, left ear, right ear, shoulder, four spine points, tail base and three tail points). All surgical and experimental procedures for mice were in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and approved by the Harvard Institutional Animal Care and Use Committee. 161 frames were labeled, making this a real-world sized laboratory dataset.