no code implementations • 7 Jun 2023 • Xieting Chu, Hongjue Zhao, Enze Xu, Hairong Qi, Minghan Chen, Huajie Shao
Experimental results demonstrate that the proposed SRCV significantly outperforms state-of-the-art baselines in discovering mathematical expressions with multiple variables.
no code implementations • 12 Oct 2022 • Enze Xu, Jingwen Zhang, Jiadi Li, Qianqian Song, Defu Yang, Guorong Wu, Minghan Chen
Alzheimer's disease (AD) is a heterogeneous, multifactorial neurodegenerative disorder characterized by beta-amyloid, pathologic tau, and neurodegeneration.
no code implementations • 1 Mar 2022 • Minghan Chen, Chunrui Xu, Ziang Xu, wei he, Haorui Zhang, Jing Su, Qianqian Song
Those genes involved in the TGF-\b{eta} pathway and their crosstalk with the ERBB pathway presented a strong survival prognosis in clinical lung cancer samples.
no code implementations • 22 Jan 2022 • Jingwen Zhang, Qing Liu, Haorui Zhang, Michelle Dai, Qianqian Song, Defu Yang, Guorong Wu, Minghan Chen
Background: Despite the striking efforts in investigating neurobiological factors behind the acquisition of amyloid-\b{eta} (A), protein tau (T), and neurodegeneration ([N]) biomarkers, the mechanistic pathways of how AT[N] biomarkers spreading throughout the brain remain elusive.
no code implementations • 7 Mar 2021 • Qing Liu, Defu Yang, Jingwen Zhang, Ziming Wei, Guorong Wu, Minghan Chen
Three major biomarkers: beta-amyloid (A), pathologic tau (T), and neurodegeneration (N), are recognized as valid proxies for neuropathologic changes of Alzheimer's disease.
no code implementations • 14 Sep 2020 • Minghan Chen, Mansooreh Ahmadian, Layne Watson, Yang Cao
To reduce model complexity, this work aims to simplify the multisite phosphorylation mechanism by a stochastic Hill function model.
no code implementations • 10 Sep 2020 • Jingwen Zhang, Defu Yang, wei he, Guorong Wu, Minghan Chen
Currently, many studies of Alzheimer's disease (AD) are investigating the neurobiological factors behind the acquisition of beta-amyloid (A), pathologic tau (T), and neurodegeneration ([N]) biomarkers from neuroimages.