no code implementations • 16 May 2019 • Yu Zheng, Hanqing Nan, Qihui Fan, Xiaochen Wang, LiYu Liu, Ruchuan Liu, Fangfu Ye, Bo Sun, Yang Jiao
During migration, individual cells can generate active pulling forces via actin filament contraction, which are transmitted to the ECM fibers through focal adhesion complexes, remodel the ECM, and eventually propagate to and can be sensed by other cells in the system.