no code implementations • 27 Nov 2019 • Geoffroy Dubourg-Felonneau, Yasmeen Kussad, Dominic Kirkham, John W Cassidy, Nirmesh Patel, Harry W Clifford
In this study, we present Flatsomatic - a Variational Auto Encoder (VAE) optimized to compress somatic mutations that allow for unbiased data compression whilst maintaining the signal.
no code implementations • 20 Nov 2019 • Geoffroy Dubourg-Felonneau, Yasmeen Kussad, Dominic Kirkham, John W Cassidy, Nirmesh Patel, Harry W Clifford
Thus, the creation of low dimensional representations of somatic mutation profiles that hold useful information about the DNA of cancer cells will facilitate the use of such data in applications that will progress precision medicine.